Results 141 to 150 of about 9,812,682 (352)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Aid effectiveness and capacity development: Implications for economic growth in developing countries [PDF]
"Although adequate country capacity is considered to be one of the critical missing factors in development outcomes, a lack of understanding of how capacity contributes to economic development and of how to account for the contribution of capacity ...
Sanyal, Prabuddha, Babu, Suresh
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Foreign direct investmant, spillovers and absorptive capacity: Evidence from quantile regressions [PDF]
This paper focuses on the role of absorptive capacity in determining whether or notdomestic firms benefit from productivity spillovers from FDI using establishment level data for the UK. We distinguish the effect of FDI in the same sector and region from
Sourafel Girma,, Holger Görg
core
How does absorptive capacity influence the origin and evolution of dynamic capabilities [PDF]
, 2010 In this thesis, I deploy a qualitative case-study method to examine the influence of a firm’s absorptive capacity of external knowledge on the origin and evolution of dynamic capabilities.
Lawer, Christopher
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, 2017 Community-based adaptation (CBA) is becoming an increasingly popular approach to climate change adaptation in the Pacific islands region. Building adaptive capacity should be an important component of projects supporting CBA.
Aalbersberg, William +4 more
core +1 more source
Analysis of Institutional Capacity in Cajamarca Region
Espacio y Desarrollo, 2014 Through this study, the Regional Government of Cajamarca has identified its actual capacities andinstitutional conditions on the basis of the national, intersectorial, sectorial, and territorial policies; of its role and competences in order to determine
Alicia Quispe Mogollón
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Entering the Union : European accession and capacity-building priorities [PDF]
The authors examine the impact of trade facilitation on bilateral trade flows. They examine trade facilitation and capacity-building priorities in 12 countries in the Europe and Central Asia region-eight of the current members of the European Union ...
Wilson, John S. +2 more
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Regions and the search for spatial justice: a question of capacity?
Regional StudiesPeer ...
Rhys Jones, Sami Moisio
openaire +2 more sources