Results 121 to 130 of about 9,812,682 (352)

Implications for the Southwest Region [PDF]

10727The advent of globalization and more integrated international trade has placed increased demandson transportation infrastructure. This report assesses the impacts of triangular trade between and amongthe United States, Brazil and China with an ...
University of Texas at Austin. Center for Transportation Research, Boske, Leigh B., Cuttino, John C.   +2 more
core  

Strengthening integrated research and capacity development within the Caribbean region

BMC International Health and Human Rights, 2011
Background The Caribbean region, like other developing regions of the world, faces significant challenges in conducting research, especially in the context of limited resource capacities and capabilities.
Dewailly Eric, Morrison Karen, Forde Martin, Badrie Neela, Robertson Lyndon   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Code designs for MIMO broadcast channels

, 2009
Recent information-theoretic results show the optimality of dirty-paper coding (DPC) in achieving the full capacity region of the Gaussian multiple-input multiple-output (MIMO) broadcast channel (BC).
Xiong, Z., Uppal, M., Stankovic, Vladimir, Xiong, Zixiang, Stankovic, V., Uppal, Momin   +5 more
core   +1 more source

Wind Speed Analysis and Capacity Factor Estimation for Bergama Region [PDF]

E3S Web of Conferences
In this research, the wind energy potential of the Bergama region is evaluated through the application of the Weibull probability distribution and corresponding capacity factor calculations.
Ozfirat Muharrem Kemal, Eyuboglu Ali Kemal   +1 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Education and Training Needs in the Field of Local Development in the Lower Danube Macro Region [PDF]

The present paper is the result of an effort made by the authors to explore the needs of education and training in the field of local development, according to the situation in Romanian and Bulgarian Danube bordering regions, aiming at designing joint ...
Nicola Yankov, Alina Elena Balalia, Laurenţiu Tăchiciu   +2 more
core  

Adverse sequelae of the COVID-19 pandemic on mental healthcare in six low- and middle-income countries (MASC): a mixed-methods study with lessons for the future

BMJ Open
Objectives The Mental health care: Adverse Sequelae of COVID-19 study aimed to (1) compare the consequences of the COVID-19 pandemic for mental health services and people with pre-existing mental health conditions (MHCs) in six low- and middle-income ...
Heidi Lempp, Katherine Sorsdahl, Atalay Alem, Charlotte Hanlon, Wubalem Fekadu, Oye Gureje, Nicole Votruba, Graham Thornicroft, Awoke Mihretu, Rubén Alvarado, Ezra Susser, Anuprabha Wickramasinghe, Elaine Brohan, Azeb Asaminew Alemu, Olatunde Olayinka Ayinde, Adekunle Adesola, Thandi Davies, Lucy Jalagania, Nino Makhashvili, Eleni Misganaw, Maria Milenova, Tamar Mujirishvili, Olha Myshakivska, Irina Pinchuk, Camila Solis-Araya, Gonzalo Soto-Brandt, Olga Toro-Devia, Shehan Williams   +27 more
doaj   +1 more source

Research on capacity region of Gaussian degraded relay broadcast channel

上海师范大学学报. 自然科学版, 2017
Considering the relay broadcast channel (RBC),the transmitter communicates with two receivers with the assistance of a relay.Based on degradation orders among the relay and the receiver outputs,three types of physically degraded RBCs (PDRBCs) model are ...
Ma Yingying, Wang Ke, Wu Youlong
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source