Results 101 to 110 of about 7,419,611 (261)
Online questionnaire to PhD candidates, Interview guide PhD students, Participant information sheet, Consent ...
Centre for Capacity Research
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Annex 1 - Master List of WHO-AFR Countries with Indicators
Master List of WHO-AFR Countries with ...
Centre for Capacity Research
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Brief on the International Conference on the Great Lakes Region [PDF]
, 2008 Document collected by the University of Texas Libraries from the web-site of the Reseau Documentaire International Sur La Region Des Grands Lacs Africains (International Documentation Network on the Great African Lakes Region).
INTERNATIONAL CONFERENCE ON THE GREAT LAKES REGION /CONFERENCE INTERNATIONALE SUR LA REGION DES GRANDS LACS
core
Playing With Reality: Emergency Capacity Building Project simulations case study
, 2012 This Emergency Capacity Building (ECB) Project simulation case study focuses on the lessons learnt from implementing the ECB Project multi-agency simulations at the national level between April 2010 and March 2012, using the ECB Simulations ...
Lumsdon, Sarah, Hockaday, David
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Analysis of Institutional Capacity in Cajamarca Region
Espacio y Desarrollo, 2014 Through this study, the Regional Government of Cajamarca has identified its actual capacities andinstitutional conditions on the basis of the national, intersectorial, sectorial, and territorial policies; of its role and competences in order to determine
Alicia Quispe Mogollón
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source