Results 101 to 110 of about 9,812,682 (352)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Near-capacity dirty-paper code design : a source-channel coding approach

, 2009
This paper examines near-capacity dirty-paper code designs based on source-channel coding. We first point out that the performance loss in signal-to-noise ratio (SNR) in our code designs can be broken into the sum of the packing loss from channel coding ...
Yang, Y., Liveris, A., Xiong, Z., Sun, Yong, Stankovic, Vladimir, Liveris, Angelos D., Xiong, Zixiang, Stankovic, V., Sun, Y., Yang, Yang   +9 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Absorptive Capacity in Practice-Based Innovation Activities: the Case of Lahti Region, Finland [PDF]

As a consequence of for example agglomeration economies, features such as good reputation and highly-skilled labour force tend to accumulate in university regions.
Vesa Harmaakorpi, Anne Paalanen, Timo Pihkala   +2 more
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Capacity building in the Asia Pacific region

, 2023
Capacity building in the countries in the Asia-Pacific region should concern anyone interested in the development of the region. Capacity building touches key aspects of life including social, political, and economic dimensions.
Kigotho, Mutuota, Mutuota, Rose
core  

The changes in diversity of vegetation and foliar stable isotopes during the terrestrial plant succession of a subtropical forest and their ecological implications

Ecological Indicators
The disturbed forest system can be restored through successional processes, where changes in the diversity of plant species serves as key indicators of processes.
Rong Fan, Chao Li, Yuting Fan, Hanfeng Xu, Huan Zhang, Lei Chen, Ninglian Wang   +6 more
doaj   +1 more source

A Numerical Study on the Capacity Region of a Three-Layer Wiretap Network. [PDF]

Entropy (Basel), 2023
Wu J, Liu N, Kang W.
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A purposeful community: the region as a focus for community capacity building

, 2014
A key defining feature of successful and sustainable communities is a clearly articulated sense of purpose. This is crucial in helping community members to identify who they are and what their communities are seeking to achieve.
Danaher, Patrick Alan, Postle, Glen David   +1 more
core