Results 41 to 50 of about 1,304,274 (289)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Hybrid Model Predictive Control Strategy of Supercapacitor Energy Storage System Based on Double Active Bridge

Energies, 2019
In order to solve the problem of which the dynamic response of a supercapacitor (SC) is limited due to the mismatch dynamic characteristics between the DC/DC converter and supercapacitor in an energy storage system, this paper proposes a hybrid model ...
Lujun Wang, Jiong Guo, Chen Xu, Tiezhou Wu, Huipin Lin   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Linking Bacillus cereus Genotypes and Carbohydrate Utilization Capacity. [PDF]

PLoS ONE, 2016
We characterised carbohydrate utilisation of 20 newly sequenced Bacillus cereus strains isolated from food products and food processing environments and two laboratory strains, B. cereus ATCC 10987 and B. cereus ATCC 14579. Subsequently, genome sequences
Alicja K Warda, Roland J Siezen, Jos Boekhorst, Marjon H J Wells-Bennik, Anne de Jong, Oscar P Kuipers, Masja N Nierop Groot, Tjakko Abee   +7 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Enterprise digital development and capacity utilization

China Accounting and Finance Review
To enrich the research on the economic consequences of enterprise digital development from the perspective of capacity utilization. Using a sample of listed firms from 2010 to 2020, this paper exploits text analysis of annual reports to construct a proxy
Hui Ma, Shenglan Chen, Xiaoling Liu, Pengcheng Wang   +3 more
doaj   +1 more source

The relationship between capacity and utilization of nonpharmacologic therapies in the US Military Health System

BMC Health Services Research, 2022
Background Nonpharmacologic therapies (NPTs) are recommended as first-line treatments for pain, however the impact of expanding professional capacity to deliver these therapies on use has not been extensively studied.
Rendelle Bolton, Grant Ritter, Krista Highland, Mary Jo Larson   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Optimization of High-Speed Rail Express Transportation Scheduling Based on Spatio-Temporal-State Network Modeling

Applied Sciences
High-speed rail express is gradually gaining attention due to its low cost and high on-time performance. This paper studied the optimization of high-speed rail express transportation modes considering passenger capacity loss.
Yuting Yang, Xiaoling Xie, Zhimei Wang
doaj   +1 more source