Results 111 to 120 of about 18,439,393 (411)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Cardiac deceleration capacity and acceleration capacity have diagnostic value in patients with vasovagal syncope regardless of age

open access: yesFrontiers in Cardiovascular Medicine
BackgroundDeceleration capacity (DC) and acceleration capacity (AC) are used to characterize autonomic regulation. The purpose of this study was to evaluate the autonomic nervous function in patients with vasovagal syncope (VVS) and to evaluate the ...
Jijing Wang   +6 more
doaj   +1 more source

On the semiadditivity of the capacities associated with signed vector valued Riesz kernels [PDF]

open access: yesarXiv, 2010
The aim of this paper is to show the semiadditivity of the capacities associated to the signed vector valued Riesz kernels of homogeneity $-\alpha$ in $\mathbb{R}^n$, with $0<\alpha
arxiv  

Measuring the Impacts of Improving Research Capacity: The Case of Training in Wheat Disease Resistance [PDF]

open access: yes
It is notoriously difficult to assess the economic value of research aimed at improving research capacity, particularly in enhancing human capital.
Brennan, John P., Quade, Kathryn J.
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

A three-threshold learning rule approaches the maximal capacity of recurrent neural networks [PDF]

open access: yes, 2015
Understanding the theoretical foundations of how memories are encoded and retrieved in neural populations is a central challenge in neuroscience. A popular theoretical scenario for modeling memory function is the attractor neural network scenario, whose ...
Alemi, Alireza   +3 more
core   +4 more sources

Recommendations for new capacity values on freeways

open access: yesPeriodica Polytechnica Civil Engineering, 2010
By the analysis of the traffic data collected loop detectors we can get information about the capacities of different freeway sections. The results and the analysis of the measurements able to show the real maximum traffic volume:2300-2400 pcphpl. According to the recent regulations the maximum tolerable traffic volumes are much lower than these and ...
István Fi, János Galuska
openaire   +3 more sources

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

open access: yesFEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston   +7 more
wiley   +1 more source

Analysis of woodchip heating capacity calculated according to technical standards and measurements of calorific value

open access: yesJournal of Forest Science, 2014
Woodchip sampling may be done according to two methodologies, based on the volume or calorific value of the fuel. The paper compares heating values obtained through relative humidity measurements according to Slovak technical standards and through ...
M. Lieskovsky   +4 more
doaj   +1 more source

The structure and predictive value of intrinsic capacity in a longitudinal study of ageing

open access: yesBMJ Open, 2019
Objectives To assess the validity of the WHO concept of intrinsic capacity in a longitudinal study of ageing; to identify whether this overall measure disaggregated into biologically plausible and clinically useful subdomains; and to assess whether total
J. Beard   +4 more
semanticscholar   +1 more source

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