Results 21 to 30 of about 6,481 (213)

Diagnósticos e prescrições de enfermagem para idosos em situação hospitalar

open access: yesAvances en Enfermería, 2015
Objetivo: Identificar os diagnósticos de enfermagem descritos pela North American Nursing Diagnosis Association mais frequentes entre idosos em situação hospitalar e propor prescrições correlatas para idosos em situação hospitalar.
Luana Nogueira Lira   +5 more
doaj   +1 more source

Authentication: A Standard Problem or a Problem of Standards? [PDF]

open access: yesPLoS Biology, 2016
Reproducibility and transparency in biomedical sciences have been called into question, and scientists have been found wanting as a result. Putting aside deliberate fraud, there is evidence that a major contributor to lack of reproducibility is ...
Amanda Capes-Davis, Richard M Neve
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

MESTRADOS PROFISSIONAIS EM ADMINISTRAÇÃO, CONTABILIDADE E TURISMO NO BRASIL E SEU PROCESSO DE AVALIAÇÃO

open access: yesRevista Gestão Universitária na América Latina, 2014
This study aimed to examine the current evaluation system of Capes for professional master's in Business Administration, Accounting and Tourism in Brazil from their own teachers and coordinators. The work is grounded in the literature of the professional
Graziela Dias Alperstedt   +3 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

OS ÍNDICES IGC, ENADE E CAPES NOS CURSOS DE ADMINISTRAÇÃO

open access: yesRevista Gestão Universitária na América Latina, 2010
Recentemente foi criado o Índice Geral de Curso (IGC) que avalia as instituições de uma maneira geral. Esse índice é gerado a partir de uma série de outros índices, bem como ENADE e CAPES.
MARIA ANDRÉA ROCHA ESCOBAR   +2 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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