Results 51 to 60 of about 788,516 (298)
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Performance Analysis of Small Refrigerating Regenerators
Heat regenerator formed by capillary and suction pipe has an important influence on the performance of small refrigeration equipment. At present, there are four main types of regenerator: capillary wear type, aluminum foil cover type, copper and tin ...
Sheng wei +3 more
doaj
Fresnel coherent diffractive imaging tomography of whole cells in capillaries
X-ray tomography can be used to study the structure of whole cells in close to their native state. Ptychographic Fresnel coherent diffractive imaging (FCDI) holds particular promise for high-resolution tomographic imaging with quantitative phase ...
Mac B Luu +13 more
doaj +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Large-amplitude capillary waves in electrified fluid sheets [PDF]
Large-amplitude capillary waves on fluid sheets are computed in the presence of a uniform electric field acting in a direction parallel to the undisturbed configuration. The fluid is taken to be inviscid, incompressible and non-conducting.
Vanden-Broeck, J, Papageorgiou, DT
core
Capillary isoelectric focusing (cIEF) and capillary zone electrophoresis (CZE) was on-line hyphenated by a dialysis interface to achieve a 2D capillary electrophoresis (CE) system.
Yang, C +4 more
core +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
The use of capillary as a sensor of cavitation
The dramatic rise in height of the meniscus within a capillary, the other end of which is immersed in a liquid undergoing ultrasonic cavitation, represents a novel, robust and inexpensive method for monitoring cavitational activity.
Leighton, T.G., Dezhkunov, N.V.
core +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source

