Results 41 to 50 of about 346,223 (313)
Skin capillary blood flow in scleroderma [PDF]
Journal of Clinical Investigation, 1971 Skin blood flow was measured by the clearance of radioactive xenon ((133)Xe) injected intracutaneously in eight patients with scleroderma and nine control subjects under conditions of controlled temperature and humidity. Scleroderma patients, on being cooled 1 hr at 18 degrees C, had a rate constant of (133)Xe clearance from the dorsal finger skin ...
E C, LeRoy, J A, Downey, P J, Cannon
openaire +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Patient-Orientated Metered Capillary Blood Collection [PDF]
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1985 A small collector bottle, with a precision-moulded top, allows capillary blood from a finger-prick to be automatically metered into a diluent for subsequent laboratory analysis. This device, which has been successfully used by patients to obtain full blood counts, glycosylated haemoglobin values and blood glucose measurements, may have wide ...
Holman, R +4 more
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Salt Sensitivity Determined From Capillary Blood [PDF]
Kidney and Blood Pressure Research, 2016 <b><i>Background/Aims: </i></b>A significant rise of blood pressure in response to a given salt load is a weak indication of high salt sensitivity, supposed to foster the development of arterial hypertension and related diseases in later life.
Hans Oberleithner, Marianne Wilhelmi
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Study of capillary transit time distribution in coherent hemodynamics spectroscopy [PDF]
Journal of Innovative Optical Health Sciences, 2015 A recently proposed analytical hemodynamic model1 [S. Fantini, NeuroImage85, 202–221 (2014)] is able to predict the changes of oxy, deoxy, and total hemoglobin concentrations (model outputs) given arbitrary changes in blood flow, blood volume, and rate ...
Angelo Sassaroli +2 more
doaj +1 more source
Preparation of isolated blood capillaries. [PDF]
Scanning microscopy, 1988 Blood capillaries have been isolated from various tissue sources yielding suspensions of capillary segments. These have provided opportunities to study the cellular properties of capillary endothelium under conditions uncomplicated by the presence of stromal tissues and in which measured parameters can be attributed to endothelial cells.
Wagner, R. C. +2 more
openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin +6 more
wiley +1 more source
A new model for the emergence of blood capillary networks
Networks and Heterogeneous Media, 2020 We propose a new model for the emergence of blood capillary networks. We assimilate the tissue and extra cellular matrix as a porous medium, using Darcy's law for describing both blood and interstitial fluid flows.
Pedro Aceves-Sanchez +7 more
doaj +1 more source