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Critical Care Research and Practice, 2012 The microcirculation is the part of the circulation where oxygen, nutrients, hormones, and waste products are exchanged between circulating blood and parenchymal cells.The microcirculation includes not only all the vessels with a diameter
Piagnarelli, Michael +2 more
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Colloids and the Microcirculation
Anesthesia & Analgesia, 2018 Colloid solutions have been advocated for use in treating hypovolemia due to their expected effect on improving intravascular retention compared with crystalloid solutions. Because the ultimate desired effect of fluid resuscitation is the improvement of microcirculatory perfusion and tissue oxygenation, it is of interest to study the effects of ...
He, Huaiwu, Liu, Dawei, Ince, Can
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Monitoring the microcirculation
Journal of Clinical Monitoring and Computing, 2012 One of the main goals of hemodynamic support is to preserve tissue perfusion. However issue perfusion is related more to microvascular perfusion than aortic blood flow. Monitoring the microcirculation has long been difficult. Recent technologic advances have made feasible monitoring of the microcirculation at bedside of critically ill patients. In this
De Backer, Daniel +2 more
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The Microcirculation: A Target for Developmental Priming
Microcirculation, 2011 There is increasing evidence that the early life environment, of which nutrition is a key component, acts through developmental adaptations to set the capacity of cardiovascular and metabolic pathways, and ultimately the limits to physiological ...
Geraldine F Clough, Mikael Norman
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Scientific Reports, 2021 The aim is to investigate that 17β-estradiol (E2)/estrogen receptors (ERs) activation normalizes splenic CD4 + T lymphocytes proliferation and cytokine production through inhibition of endoplasmic reticulum stress (ERS) following hemorrhage.
Peng Wang +14 more
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Cardiovascular Therapeutics, 2023 Mounting evidence has confirmed that essential hypertension (EH) is closely related to low-grade inflammation, but there is still a lack of in-depth understanding of the state of immune cells in the circulating blood of patients with EH.
Rui Yang +7 more
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The Impact of Thrombo‐inflammation on the Cerebral Microcirculation [PDF]
, 2021 Copyright © 2021 The Authors. The intertwined processes of thrombosis and inflammation (termed “thrombo-inflammation”) are significant drivers of cerebrovascular diseases, and as such, they represent prime targets for drug discovery programs focusing on ...
Gavins, FNE, Ansari, J
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Frontiers in Immunology, 2022 PurposePost hemorrhagic shock mesenteric lymph (PHSML) return contributes to CD4+ T cell dysfunction, which leads to immune dysfunction and uncontrolled inflammatory response.
Hui-Bo Du +27 more
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Phenotyping the Microcirculation [PDF]
Hypertension, 2012 The role of the microcirculation is increasingly being recognized in the pathophysiology of cardiovascular disease.1,2 The microcirculation is a major site of damage in most target organs of cardiovascular disease, such as the heart, brain, and kidney. Both functional and structural alterations in the small arteries, arterioles, and capillaries are the
Struijker-Boudier, Harry A.J. +3 more
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Interaction of Estradiol and Endoplasmic Reticulum Stress in the Development of Esophageal Carcinoma
Frontiers in Endocrinology, 2020 Gender differences in esophageal cancer patients indicate that estradiol may have antitumor effects on esophageal cancer. The initiation of endoplasmic reticulum stress (ERS) can induce apoptosis in esophageal cancer cells.
Chen Wang +10 more
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