Results 31 to 40 of about 100,018 (314)

Ameliorating effects of traditional Chinese medicine preparation, Chinese materia medica and active compounds on ischemia/reperfusion-induced cerebral microcirculatory disturbances and neuron damage

open access: yesActa Pharmaceutica Sinica B, 2015
Ischemic stroke and ischemia/reperfusion (I/R) injury induced by thrombolytic therapy are conditions with high mortality and serious long-term physical and cognitive disabilities. They have a major impact on global public health.
Kai Sun, Jingyu Fan, Jingyan Han
doaj   +1 more source

Growth differentiation factor 11 attenuates cardiac ischemia reperfusion injury via enhancing mitochondrial biogenesis and telomerase activity

open access: yesCell Death and Disease, 2021
It has been reported that growth differentiation factor 11 (GDF11) protects against myocardial ischemia/reperfusion (IR) injury, but the underlying mechanisms have not been fully clarified.
Lin Chen   +15 more
doaj   +1 more source

Astaxanthin Attenuates Homocysteine-Induced Cardiotoxicity in Vitro and in Vivo by Inhibiting Mitochondrial Dysfunction and Oxidative Damage

open access: yesFrontiers in Physiology, 2017
Homocysteine (Hcy) as an independent risk factor contributes to the occurrence and development of human cardiovascular diseases (CVD). Induction of oxidative stress and apoptosis was commonly accepted as the major mechanism in Hcy-induced cardiotoxicity.
Cun-dong Fan   +8 more
doaj   +1 more source

Non-invasive imaging of microcirculation: a technology review. [PDF]

open access: yes, 2014
Microcirculation plays a crucial role in physiological processes of tissue oxygenation and nutritional exchange. Measurement of microcirculation can be applied on many organs in various pathologies.
Sturesson, Christian   +5 more
core   +1 more source

The effect of blood transfusion on sublingual microcirculation in critically ill patients: A scoping review

open access: yes, 2021
Purpose: To investigate the effects of red blood cell (RBC) transfusion on sublingual microcirculation in critically ill patients. Methods: Systematic strategy was conducted to search studies that measured sublingual microcirculation before and after ...
Can Ince   +7 more
core   +1 more source

Mesenteric Lymph Drainage Alleviates Acute Kidney Injury Induced by Hemorrhagic Shock without Resuscitation

open access: yesThe Scientific World Journal, 2014
This study aimed to investigate the effect of mesenteric lymph drainage on the acute kidney injury induced by hemorrhagic shock without resuscitation. Eighteen male Wistar rats were randomly divided into sham, shock, and drainage groups.
Zi-Gang Zhao   +4 more
doaj   +1 more source

Insights into the toxicological effects of nanomaterials on atherosclerosis: mechanisms involved and influence factors

open access: yesJournal of Nanobiotechnology, 2023
Atherosclerosis is one of the most common types of cardiovascular disease and is driven by lipid accumulation and chronic inflammation in the arteries, which leads to stenosis and thrombosis.
Siyu Chen   +11 more
doaj   +1 more source

Evaluation of cutaneous microcirculation in systemic sclerosis. An update

open access: yes, 2023
The impairment of the microcirculation is a crucial aspect of systemic sclerosis which manifests as a plethora of vascular abnormalities. This review examines the methods used in the evaluation of the changes to the microcirculation.
Katarzyna Pawlik   +6 more
core   +1 more source

Schisandrin Attenuates Lipopolysaccharide-Induced Lung Injury by Regulating TLR-4 and Akt/FoxO1 Signaling Pathways

open access: yesFrontiers in Physiology, 2018
Objective: Acute lung injury is a severe clinic condition with limited therapeutic approaches. This study evaluated whether schisandrin (Sch), an ingredient of Schisandra chinensis, has preventive effects on endothelium and epithelium injury induced by ...
Kai Sun   +14 more
doaj   +1 more source

The Regulatory Role of GBF1 on Osteoclast Activation Through EIF2a Mediated ER Stress and Novel Marker FAM129A Induction

open access: yesFrontiers in Cell and Developmental Biology, 2021
Bone-resorbing activities of osteoclasts (OCs) are highly dependent on actin cytoskeleton remodeling, plasma membrane reorganization, and vesicle trafficking pathways, which are partially regulated by ARF-GTPases.
Cailing Wen   +12 more
doaj   +1 more source

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