Results 51 to 60 of about 100,018 (314)

Microvascular damage is associated with carotid wall structural changes in Systemic Sclerosis: a capillaroscopy and ultrasound‐based observational study

Arthritis Care &Research, Accepted Article.
Introduction Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli, Luca Clerici, Francesco Lapia, Giusy C. Moltisanti, Eleonora Zaccara, Greta Pellegrino, Daniela Bompane, Francesca Capelli, Letizia Ferrami, Laura Castelnovo, Antonio Tamburello, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +13 more
wiley   +1 more source

Improving vasculoprotective effects of MSCs in coronary microvessels – benefits of 3D culture, sub-populations and heparin

Frontiers in Immunology, 2023
IntroductionOpening occluded coronary arteries in patients with myocardial infarction (MI) damages the delicate coronary microvessels through a process called myocardial ischaemia-reperfusion injury.
Kobkaew Bumroongthai, Dean P. J. Kavanagh, Paul Genever, Neena Kalia   +3 more
doaj   +1 more source

Extended‐volume image‐derived models of coronary microcirculation

, 2023
ObjectiveRecent advances in tissue clearing and high-throughput imaging have enabled the acquisition of extended-volume microvasculature images at a submicron resolution.
Sy, Christine Lauren, Vigneshwaran, Vibujithan, Vibujithan Vigneshwaran, Sands, Gregory B, Christine Lauren Sy, Gregory B. Sands, Bruce H. Smaill, Nicolas P. Smith, Smith, Nicolas P, Smaill, Bruce H   +9 more
core   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Effects of sevoflurane and desflurane on microcirculation during non-cardiac surgery

, 2021
Objectives: Assessment of microcirculation is thought to be a surrogate of tissue perfusion and anesthetic drugs are known to alter the microcirculation in cardiac surgery patients, but their effects in less complicated non-cardiac surgery remain unknown.
Cizmeci, Elif A., Kanbak, Meral, Ince, Can, Cil, Hemra, Kilicaslan, Banu   +4 more
core  

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Performance Review of Multiple Reference Versus Time Domain Optical Coherence Tomography

IEEE Photonics Journal, 2018
We present a detailed characterization of noise sources in multiple reference optical coherence tomography (MR-OCT) compared to time-domain OCT (TD-OCT).
Kai Neuhaus, Paul M. McNamara, Sergey Alexandrov, Sean O'Gorman, Josh Hogan, Carol Wilson, Martin J. Leahy   +6 more
doaj   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

Advanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu   +8 more
wiley   +1 more source

Algorithm‐Based Common Microcirculatory Framework for Monitoring and Visualizing the Integrated Pancreatic Microcirculation in Type 2 Diabetes Mellitus Mice

Journal of Diabetes
Background Recent research has challenged the viewpoint that pancreatic islets operate independently of surrounding exocrine tissues, revealing a bidirectional blood flow between the endocrine and exocrine pancreas.
Yuan Li, Yingyu Wang, Bing Wang, Weiqi Liu, Mengting Xu, Xiaoyan Zhang, Xueting Liu, Hao Ling, Xu Zhang, Mingming Liu, Ruijuan Xiu   +10 more
doaj   +1 more source

Exosomes Derived From Pericytes Improve Microcirculation and Protect Blood–Spinal Cord Barrier After Spinal Cord Injury in Mice

Frontiers in Neuroscience, 2019
Spinal cord injury (SCI) often leads to severe and permanent paralysis and places a heavy burden on individuals, families, and society. Until now, the therapy of SCI is still a big challenge for the researchers. Transplantation of mesenchymal stem cells (
Xiaochen Yuan, Qingbin Wu, Peng Wang, Yingli Jing, Haijiang Yao, Yinshan Tang, Zhigang Li, Honggang Zhang, Ruijuan Xiu   +8 more
doaj   +1 more source