Results 51 to 60 of about 29,995 (215)

Algorithm‐Based Common Microcirculatory Framework for Monitoring and Visualizing the Integrated Pancreatic Microcirculation in Type 2 Diabetes Mellitus Mice

Journal of Diabetes
Background Recent research has challenged the viewpoint that pancreatic islets operate independently of surrounding exocrine tissues, revealing a bidirectional blood flow between the endocrine and exocrine pancreas.
Yuan Li, Yingyu Wang, Bing Wang, Weiqi Liu, Mengting Xu, Xiaoyan Zhang, Xueting Liu, Hao Ling, Xu Zhang, Mingming Liu, Ruijuan Xiu   +10 more
doaj   +1 more source

Exosomes Derived From Pericytes Improve Microcirculation and Protect Blood–Spinal Cord Barrier After Spinal Cord Injury in Mice

Frontiers in Neuroscience, 2019
Spinal cord injury (SCI) often leads to severe and permanent paralysis and places a heavy burden on individuals, families, and society. Until now, the therapy of SCI is still a big challenge for the researchers. Transplantation of mesenchymal stem cells (
Xiaochen Yuan, Qingbin Wu, Peng Wang, Yingli Jing, Haijiang Yao, Yinshan Tang, Zhigang Li, Honggang Zhang, Ruijuan Xiu   +8 more
doaj   +1 more source

Microcirculation [PDF]

, 2012
The microcirculation is the part of the circulation where oxygen, nutrients, hormones, and waste products are exchanged between circulating blood and parenchymal cells.The microcirculation includes not only all the vessels with a diameter
Piagnarelli, Michael, Piagnerelli, Michaël, Dubin, A. (Arnaldo), Can Ince, Piagnerelli, M. (Michael), Dubin, Arnaldo, Ince, C. (Can), Michael Piagnerelli, Ince, Can, Arnaldo Dubin   +9 more
core   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Low‐Intensity Ultrasound‐Triggered Microbubble Cavitation Attenuates Diabetic Kidney Injury Partially by Reversing Endothelial Dysfunction

Advanced Science, EarlyView.
Non‐invasive low‐intensity pulsed ultrasound ‐triggered cavitation of clinically approved diagnostic‐grade microbubbles delivers favorable mechanical stimuli to renal microvasculature. This intervention restores renal microvascular homeostasis, alleviates DKD‐associated histological and functional damage, and suppresses inflammatory and fibrotic ...
Yubo Lai, Liang Zhang, Wenxin Tao, Jieyuan An, Lantian Wang, Zhaoyou Liu, Guodong Yang, Pengying Wu, Lijun Yuan   +8 more
wiley   +1 more source

Comparative study of the effects of cigarette smoke versus next generation tobacco and nicotine product extracts on endothelial function

Redox Biology, 2021
Tobacco smoking and hemodynamic forces are key stimuli for the development of endothelial dysfunction. As an alternative to smoking, next generation tobacco and nicotine products (NGP) are now widely used.
Sindy Giebe, Anja Hofmann, Melanie Brux, Frazer Lowe, Damien Breheny, Henning Morawietz, Coy Brunssen   +6 more
doaj   +1 more source

In Situ Photo‑Crosslinked Functional Bilayer Hydrogel Modulates Local Microenvironment and Remyelination After Optic Nerve Injury

Advanced Science, EarlyView.
A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan, Yate Huang, Junhao Zhang, Shudong Tian, Zhixing Li, Xuanwen Li, Yanchen Zhang, Dongmei Wang, Sihao Ye, Ming Jin, Neng Ling, Wentao Yan, Kaihui Nan, Wencan Wu   +13 more
wiley   +1 more source

A multi-organ atlas of microcirculatory signatures for systemic profiling of diabetic and therapeutic states

Scientific Data
Microcirculatory deterioration in diabetes mellitus causes severe organ-specific complications, yet a systemic understanding of its cross-organ pathophysiology remains elusive due to a lack of comprehensive data.
Yuan Li, Weiqi Liu, Yingyu Wang, Bing Wang, Xiang Xu, Bingwei Li, Xu Zhang, Mingming Liu   +7 more
doaj   +1 more source

Selenium-Containing Protein From Selenium-Enriched Spirulina platensis Attenuates Cisplatin-Induced Apoptosis in MC3T3-E1 Mouse Preosteoblast by Inhibiting Mitochondrial Dysfunction and ROS-Mediated Oxidative Damage

Frontiers in Physiology, 2019
Accumulated evidences have verified that cancer chemotherapy may increase the risk of osteoporosis and severely affected the life quality. Osteoclasts hyperactivation was commonly accepted as the major pathogenesis of osteoporosis.
Jing-yi Sun, Ya-jun Hou, Xiao-yan Fu, Xiao-ting Fu, Jin-kui Ma, Ming-feng Yang, Bao-liang Sun, Cun-dong Fan, Jinrok Oh   +8 more
doaj   +1 more source

Associations of Menstrual Cycle Regularity and Length With Cardiovascular Diseases: A Prospective Study From UK Biobank

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background The association between menstrual cycle characteristics and cardiovascular outcomes remains unclear. This study was undertaken to evaluate whether menstrual cycle regularity and length throughout the life course are associated with ...
Chensihan Huang, Bingquan Lin, Youwen Yuan, Kangli Li, Bingyan Xu, Peizhen Zhang, Xueyun Wei, Weiwei Wang, Wenhui Liu, Yajuan Deng, Deying Liu, Jiayang Lin, Yan Huang, Huijie Zhang   +13 more
doaj   +1 more source