ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
Capillary Electrophoresis-Mass Spectrometry for Top-Down Proteomics. [PDF]
Wang Q, Wang Q, Zhu G, Sun L.
europepmc +1 more source
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Reproducible Capillary Electrophoresis-Mass Spectrometry-Based Top-Down Proteomics of Complex Proteomes Enabled by an Advanced Cationic Polymer Coating. [PDF]
Gao G +7 more
europepmc +1 more source
Recent Advances in Top‐Down Proteomics for Single‐Cell Research
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley +1 more source
Development of a Dye-Binding Method for Nanoplastics Detection in Snow Samples Using Capillary Electrophoresis with Laser-Induced Fluorescence Detection. [PDF]
Lai EPC +3 more
europepmc +1 more source
Comparison of Capillary Electrophoresis and HPLC-Based Methods in the Monitoring of Moniliformin in Maize. [PDF]
Astolfi S +7 more
europepmc +1 more source
Characterization of the Specific Binding Between Aptamers and Cytochrome c With Pressure-Assisted Capillary Electrophoresis Frontal Analysis. [PDF]
Wang S, Li C, Wang S, Li H, Chen DDY.
europepmc +1 more source
Development of a Green Capillary Electrophoresis Method for Determining and Quality Control of Dapagliflozin: An Oral Hypoglycemic Agent. [PDF]
Bueno LM +4 more
europepmc +1 more source
Capillary Electrophoresis Mass Spectrometry Interfacing via Multifunctional Vibrating Sharp Edge Ionization Spray for the Simultaneous Delivery of an Auxiliary Flow, Analyte Mixing, and Fluid Nebulization. [PDF]
Elshamy YS, Holland LA, Corley EL.
europepmc +1 more source

