Results 181 to 190 of about 98,360 (263)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

How to perform fluid de-escalation in critical care. [PDF]

open access: yesAnn Intensive Care
Bircher RE   +3 more
europepmc   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi   +9 more
wiley   +1 more source

Analysis of the usefulness and benefits of ultrafiltration in cardiorenal syndrome: A systematic review

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1194-1202, April 2025.
Abstract Aims Cardiac decompensation in cardiorenal syndrome (CRS) results in systemic congestion usually treated with diuretics. When despite high doses of diuretics, response is poor, ultrafiltration (UF) appears to be a useful and safe technique.
Borja Guerrero Cervera   +12 more
wiley   +1 more source

Albumin 20% in surgical and critically ill patients; a comprehensive review. [PDF]

open access: yesCrit Care
Hahn RG   +4 more
europepmc   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara   +7 more
wiley   +1 more source

Recovery Factor of Pure Helium Injection in Depleted Gas Reservoirs and Its Influencing Factors

open access: yesEnergy Science &Engineering, EarlyView.
This study employs compositional numerical simulation to systematically investigate the effects of injection rate, production rate, storage duration, and injection‐production scheme on pure helium recovery in depleted gas reservoirs. Low injection rates reduce viscous fingering while high production rates maximize near‐wellbore helium extraction ...
Shijie Zhu   +6 more
wiley   +1 more source

A blood-brain barrier model based on flexible tubes to tailor the biophysical and chemical environment for drug delivery testing. [PDF]

open access: yesMater Today Bio
Alexaki M   +7 more
europepmc   +1 more source

The Seepage Characteristics of Single Rough Joint of Granite Based on NMR Technology: A Modified Cubic Law

open access: yesEnergy Science &Engineering, EarlyView.
The low‐field nuclear magnetic resonance (NMR) measurements are applied to investigate the seepage characteristics of the single rough joint. The purpose of this paper is to investigate the seepage characteristics of granite specimens with single‐joint channel under the different roughness, confining pressures and seepage pressures.
Hao Cheng, Xiujie Zhong
wiley   +1 more source

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