Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development
Advanced Science, EarlyView.Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu +8 more
wiley +1 more source
Study on the Seepage Model and Evaluation System of Coal Seam Water Injection Considering Fracture Aperture and Surface Roughness. [PDF]
ACS OmegaSun K, Xu H, Wang E, Xue M, Chen X.
europepmc +1 more source
Advanced Science, EarlyView.This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu +11 more
wiley +1 more source
Evaluation of lateral sealing capability of fault-controlled gas storage at different periods. [PDF]
Sci RepMeng L +7 more
europepmc +1 more source
MAPK Signaling and Angiopoietin-2 Contribute to Endothelial Permeability in Capillary Malformations [PDF]
Sana Nasim +10 more
openalex +1 more source
AI‐Driven Acceleration of Fluorescence Probe Discovery
Advanced Science, EarlyView.We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang +18 more
wiley +1 more source
Re-Valorizing Oyster-Shell Waste in Natural Hydraulic Lime-Based Mortars for Brick Substrate Applications: Performance and Durability. [PDF]
Materials (Basel)Bellei P +4 more
europepmc +1 more source
Advanced Science, EarlyView.We show that solutal Marangoni flows in thin films climbing the outer surfaces of hydrophilic obstacles break circular Belousov‐Zhabotinsky waves into striking flower‐like patterns. Evaporation‐driven surface‐tension gradients, coupled with gravity, trigger the instability; above a threshold, petal number scales linearly with obstacle diameter ...
Sangram Gore +9 more
wiley +1 more source
Specificity of endothelial cells in endothelial dysfunction of diabetic kidney disease and their crosstalk with neighboring cells: an updated review. [PDF]
Front Endocrinol (Lausanne)Li J +9 more
europepmc +1 more source