Results 31 to 40 of about 2,586,634 (308)

Using multiple cause of death information to eliminate garbage codes

Demographic Research, 2021
Background: International comparisons of mortality largely depend on the quality of data. With more than 20Š of deaths annually assigned to ill-defined cardiovascular conditions, the mortality level due to well-defined causes of death is under-registered
Agnieszka Fihel, Magdalena Muszyńska-Spielauer   +1 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

How much time is left? International trends in parenthood expectancy

Demographic Research, 2023
Background: Many industrialized societies have experienced increases in life expectancy and in the mean age at first birth (MAFB). This has likely impacted the lifetime that parents share with their children; i.e., parenthood expectancy (PEX ...
Erich Striessnig, Alessandra Trimarchi
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

An open-source approach for measuring corporate impacts on ecosystem services and biodiversity

Communications Earth & Environment
Existing approaches to evaluating companies on sustainability-related issues include limited accounting of impacts on nature and its contributions to human well-being.
Lisa Mandle, Andrew Shea, Emily Soth, Jesse A. Goldstein, Stacie Wolny, Jeffrey R. Smith, Rebecca Chaplin-Kramer, Richard P. Sharp, Mayur Patel   +8 more
doaj   +1 more source

Thresholds for clinical practice that directly link handgrip strength to remaining years of life: estimates based on longitudinal observational data

BMJ Open, 2022
Objective Muscle strength is a powerful predictor of mortality that can quickly and inexpensively be assessed by measuring handgrip strength (HGS). What is missing for clinical practice, however, are empirically meaningful cut-off points that apply to ...
Sergei Scherbov, Sonja Spitzer, Nadia Steiber   +2 more
doaj   +1 more source

Towards reviving post-Olympic Athens as a cultural destination [PDF]

, 2012
This paper examines the effects of global change on the status and qualities of the Greek national capital, Athens, focusing on how they affect the development of cultural tourism in the city.
Alevizopoulou M., Apostolopoulos Y., Arksey H., Asprogerakas E., Denzin N. K., Georgios Boustras, Glaser B. G., Graham B., Hall C. M., King N., Koutoulas D., Leontidou L., Leontidou L., Maitland R., McKercher B., Meethan K., Miles M., Morgan N., Nikolaos Boukas, Papageorgiou-Venetas A., Shaw G., Theobald W. F., Van der Borg J., Vassilios Ziakas, Weed M., Wickens E., Yin R. K.   +26 more
core   +2 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Survival and Years of Good Life in Finland in the very long run

Finnish Yearbook of Population Research, 2020
In this paper we apply the recently developed wellbeing indicator ‘Years of Good Life’ (YoGL) to Finland, which has the world’s longest annual demographic time series starting in 1722. We combine this with scenarios up to 2100 as developed under the SSP (
Claudia Reiter, Wolfgang Lutz
doaj   +1 more source

HOW WELL DOES SATELLITE FINE MODE AEROSOL PRODUCT VALIDATE WITH GROUND-BASED MEASUREMENTS FOR MODIS AND HIMAWARI-8? [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2018
Currently, the validation of MODIS and Himawari-8 aerosol products mostly focuses on AOD, but the validation of their fine mode aerosol data is limited. In this paper, 22 AERONET sites in Asia from 2015 to 2016 were selected to validate the MODIS and the
J. Jin, J. Jin, J. Jin, X. Yang, C. Liang, C. Liang, W. Zhao, Z. Li, Z. Li, X. Yan, X. Yan   +10 more
doaj   +1 more source