Results 131 to 140 of about 6,103,803 (245)

Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma

Advanced Science, EarlyView.
Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul, Alexandra Moreno Mitchell, Dean O'Neil, Yutong Luo, Khuloud T. Al‐Jamal   +4 more
wiley   +1 more source

Biodiversity and natural capital in ecologically sensitive regions. [PDF]

Sci Rep
Chettry V, Kumar R, Testa R.
europepmc   +1 more source

Detaching Photosensitive Nanoparticles from Cells Prevents Them from Remaining in Cells after Photoporation

Advanced Science, EarlyView.
Phenylboronic acid‐functionalized gold nanoparticles reversibly attach to cell‐surface glycans, enhancing photoporation‐mediated intracellular delivery. After irradiation, ATP competitively disrupts the boronic ester interactions and removes cell‐associated nanoparticles, markedly reducing residual gold.
Tao Lu, Mina Nikolić, Baihao Huang, Deep Punj, Herlinde De Keersmaecker, Thibaut Van Acker, Wenjia Xie, Florian Vanlauwe, Phillip Blondeel, Liesl De Graeve, Félix Sauvage, Ranhua Xiong, Chaobo Huang, Frank Vanhaecke, Kevin Braeckmans, Stefaan C. De Smedt   +15 more
wiley   +1 more source

Social capital and community resilience to socio-natural hazards in informal settlements of Chile's extractive north: city of Copiapó, Atacama region, Chile. [PDF]

Front Public Health
Contreras Y, Pérez M.
europepmc   +1 more source

LEARNING EFFECT AND SOCIAL CAPITAL: A CASE STUDY OF NATURAL DISASTER FROM JAPAN [PDF]

Using Japanese prefecture level data for the years between 1988 and 2001, this paper explores how and the extent to which social capital has an effect on the damage resulting from natural disasters.
yamamura, eiji
core  

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

Driving mechanisms of forest ecological product value realization using fsQCA analysis of 43 cases in China. [PDF]

Sci Rep
Zhu X, Wang W, Shi Q, Zhao F, Zheng Z.
europepmc   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

Changes in the Distribution of General Physicians in Korea During the 2024-2025 Medical Crisis: A Descriptive Analysis Using Nationwide HIRA Data. [PDF]

J Korean Med Sci
Park JY, Lee SG.
europepmc   +1 more source

Natural capital risk management: regulating the main externalities of business

, 2015
Natural capital is being used at an unsustainable rate, yet the regulatory response is ad hoc, piecemeal and insufficient to address the scale of the problem.
Martin, Rhett
core