Results 161 to 170 of about 7,675,198 (323)
Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries
Advanced Science, EarlyView.While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang +3 more
wiley +1 more source
Sustainability and Substitution of Exhaustible Natural Resources: How Resource Prices Affect Long-Term R&D Investments [PDF]
Traditional resource economics has been criticised for assuming too high elasticities of substitution, not observing material balance principles and relying too much on planner solutions to obtain long-term growth.By analysing a multi-sector R&D based ...
Bretschger, L., Smulders, J.A.
core +1 more source
Advanced Science, EarlyView.Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang +7 more
wiley +1 more source
Mechanisms of capital endowment's influence on farmers' adoption of low-carbon fertilization technologies. [PDF]
Sci RepYuan Y, Sun L, Chen S, She Z, Niu H.
europepmc +1 more source
Advanced Science, EarlyView.In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao +6 more
wiley +1 more source
How does livelihood capital alleviate psychological anxiety among immigrants? [PDF]
Front Public HealthJin H, Liu H.
europepmc +1 more source
BUILDING SYNTHETIC INDICATORS FOR ASPECTS OF TERRITORIAL CAPITAL TOWARDS THEIR IMPACT ON REGIONAL PERFORMANCE [PDF]
Empirical analyses highlight local structural features (territorial capital) as constraints on regional growth and interregional convergence processes, but scant attention is devoted to traditional localised resources and specifically the natural and ...
Michela Martinoia, Tomaso Pompili
core
Advanced Science, EarlyView.Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu +8 more
wiley +1 more source
Measuring disaster resilience in MENA countries and its impact on disaster losses. [PDF]
Sci RepDemir A, Dinçer AE, Dincer NN.
europepmc +1 more source
Liquidity Trap Prevention and Escape: A Simple Proposition [PDF]
Liquidity traps occur when the natural nominal interest rate becomes negative. In a model with capital price dynamics explicitly considered, we find that shocks in the future can cause current and lasting liquidity traps. We propose that the central bank
Junning Cai
core