Results 141 to 150 of about 84,218 (260)

Multiobjective Environmental Cleanup with Autonomous Surface Vehicle Fleets Using Multitask Multiagent Deep Reinforcement Learning

Advanced Intelligent Systems, EarlyView.
This study presents a multitask strategy for plastic cleanup with autonomous surface vehicles, combining exploration and cleaning phases. A two‐headed Deep Q‐Network shared by all agents is traineded via multiobjective reinforcement learning, producing a Pareto front of trade‐offs.
Dame Seck, Samuel Yanes, Manuel Perales, Daniel Gutiérrez, Sergio Toral   +4 more
wiley   +1 more source

The mRNA-Based Innovative Strategy: Progress and Challenges. [PDF]

Nanomicro Lett
Zhou H, Wei D, Chen Z, Chen H, Dong C, Yao W, Wang J, Liu X, Li Y, Yang Y, Tan W.   +10 more
europepmc   +1 more source

Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3' UTRs Identified by Cellular Library Screening.

Molecular Therapy, 2019
Alexandra G Orlandini von Niessen, Marco A. Poleganov, C. Rechner, Arianne Plaschke, L. Kranz, Stephanie Fesser, M. Diken, M. Löwer, Britta Vallazza, T. Beissert, V. Bukur, A. Kuhn, Ö. Türeci, U. Şahin   +13 more
semanticscholar   +1 more source

AI‐Driven Predictive Design and Functionalization of Three Dimensional‐Printed PEEK Implants with Tryptophan‐Enriched Alginate Hydrogel for Enhanced Biomimetic Surface Performance

Advanced Intelligent Systems, EarlyView.
This study introduces an AI‐guided strategy to design 3D‐printed PEEK implants functionalized with a tryptophan‐enriched alginate hydrogel (TRYALPEEK). The modification improves hydrophilicity, reduces surface roughness, enhances cytocompatibility, and optimizes stress distribution. The platform offers a promising route for personalized implant design,
Wafa Benaatou, Desirae Nance, Denisse A Gutierrez, Renato J Aguilera, Armando Varela‐Ramirez, Filiz Yagci, Emir Esim, Mahesh Narayan, Mohamed Noufal   +8 more
wiley   +1 more source

Trans-complementation of chikungunya virus replicase mutants reveals alphavirus replication complexity and supports antiviral tool development. [PDF]

PLoS Pathog
Wang S, Naumenko K, Mirzajani Sarvandani M, Lello LS, Makhotina A, Claesson HC, Žusinaite E, Merits A.   +7 more
europepmc   +1 more source

Ultra‐Efficient Kidney Stone Fragment Removal via Spinner‐Induced Synergistic Circulation and Spiral Flow

Advanced Intelligent Systems, EarlyView.
Leveraging spinning‐induced localized suction, the spinner device enables ultra‐efficient removal of kidney stone fragments, capturing a larger quantity of fragments from distances exceeding 20 mm. The spinner significantly improves the efficiency and effectiveness of stone fragment removal by reducing operative time, increasing stone‐free rates, and ...
Yilong Chang, Jasmine Guadalupe Vallejo, Yangqing Sun, Ruike Renee Zhao   +3 more
wiley   +1 more source

Modular Synthetic Platform for the Elaboration of Fragments in Three Dimensions for Fragment-Based Drug Discovery. [PDF]

J Am Chem Soc
Gomez-Angel AR, Klein HF, Yao SY, Donald JR, Firth JD, Appiani R, Palmer CJ, Lincoln J, Lucas SCC, Fusani L, Storer RI, O'Brien P.   +11 more
europepmc   +1 more source

Automated Discovery of Multicellular Behavior for Optimized Plant Growth and Climate Resilience

Advanced Intelligent Systems, EarlyView.
An automated robotic system is described for rapid scientific experimentation with multicellular organisms. By enhancing a robotic liquid handler with a custom developed deep learning algorithm and camera module, samples and data are prepared with minimal human intervention.
Mark A. DeAngelis, Philip R. LeDuc, Warren C. Ruder   +2 more
wiley   +1 more source

SmartDetectAI: An AI‐Powered Web App for Real‐Time Colorimetric Detection of Heavy Metals in Water

Advanced Intelligent Systems, EarlyView.
SmartDetectAI integrates silver nanoparticle‐based colorimetric sensing with an AI‐powered web app for rapid, on‐site detection of toxic heavy metals in water. By combining aggregation‐driven optical changes with machine learning analysis of red ‐ green ‐ blue values, the platform achieves portable, low‐cost, and accurate monitoring of Hg‐ and Cd‐based
Nishat Tasnim, Mirza M. A. Tunur, Fahad Arefin, Shahad Saroar, Md. Wahadoszamen, Taslim Ur Rashid, Aminul I. Talukder, Md. Nurul Amin, Mahmudur Rahman, Ahsan Habib   +9 more
wiley   +1 more source

Comprehensive self-antigen screening to assess cross-reactivity in promiscuous T-cell receptors. [PDF]

Front Immunol
Sharma G, Teng F, Round J, Sneddon SA, Sivasothy S, Brown SD, Holt RA.   +6 more
europepmc   +1 more source