Results 151 to 160 of about 84,218 (260)

BeeRootBot: A Bioinspired Robotic Probe Exhibiting Apical Growth through In Situ Soil Binding

Advanced Intelligent Systems, EarlyView.
This study introduces a novel method for consolidating subterranean exploration pathways in plant‐inspired robots by binding in‐situ soil with beeswax, a biobased material. This simultaneous advancement and wall‐lining process reduces penetration resistance, enhances exploration efficiency, enables communication and resource sharing, and promotes ...
Sachin Sachin, Alessio Mondini, Stefano Mariani, Emanuela Del Dottore, Barbara Mazzolai   +4 more
wiley   +1 more source

Discovery of a Promising Hydroxyamino-Piperidine HDAC6 Inhibitor via Integrated Virtual Screening and Experimental Validation in Multiple Myeloma. [PDF]

Pharmaceuticals (Basel)
Chiera F, Curcio A, Rocca R, Valentino I, Gentile M, Alcaro S, Amodio N, Artese A.   +7 more
europepmc   +1 more source

Biomarker‐Agnostic Detection of Ovarian Cancer from Blood Plasma Using a Machine Learning‐Driven Electronic Nose

Advanced Intelligent Systems, EarlyView.
This study introduces a biomarker‐agnostic diagnostic strategy for ovarian cancer, utilizing a machine learning‐enhanced electronic nose to analyze volatile organic compound signatures from blood plasma. By overcoming the dependence on specific biomarkers, this approach enables accurate detection, staging, and cancer type differentiation, offering a ...
Ivan Shtepliuk, Lingyin Meng, Christer Borgfeldt, Jens Eriksson, Donatella Puglisi   +4 more
wiley   +1 more source

The Use of Computational Approaches to Design Nanodelivery Systems. [PDF]

Nanomaterials (Basel)
Abughalia A, Flynn M, Clarke PFA, Fayne D, Gobbo OL.   +4 more
europepmc   +1 more source

A Novel Milli‐Scale Magnetic Robot Exploiting Rotation for Controlled Magnetic Particles Release

Advanced Intelligent Systems, EarlyView.
Delivering magnetic particles can become a game changer in minimally invasive medicine. To cope with this challenge, a magnetically actuated milli‐scale carrier leveraging rotation to perform on‐demand tunable release of magnetic particles across multiple release events is presented.
Giordano De Angelis, Tamerlan Srymbetov, Arianna Menciassi, Veronica Iacovacci   +3 more
wiley   +1 more source

Identification of skeletal muscle stem cell adhesion motifs using spot-synthesis-based peptide arrays. [PDF]

iScience
Leblanc E, Schüler SC, Liu Y, Théroux L, Le Moal E, Bonin MA, Boudreault PL, Bentzinger CF.   +7 more
europepmc   +1 more source

Stimuli‐Responsive Electrofluidic Nervous System for Autonomous Soft Robots

Advanced Intelligent Systems, EarlyView.
A stimuli‐responsive electrofluidic nervous system (SENS) is introduced to achieve sensing, signal processing, and decision‐making using soft materials. Comprising fluidic switches and electroactive actuators, SENS enables multimodal stimuli‐responsiveness and autonomous control in soft robots.
Dip Kumar Saha, Dana Ragab, Nicolas Herzig, Hareesh Godaba   +3 more
wiley   +1 more source

Discovery of a First‐in‐Class Covalent Allosteric SHP1 Inhibitor with Immunotherapeutic Activity

Angewandte Chemie, EarlyView.
A covalent allosteric inhibitor M029 was discovered for SHP1, a novel target for immunotherapy. M029 binds to a cryptic Cys remote from the active site, exhibits robust target engagement, and blocks tumor progression by stimulating antitumor immune response.
Zihan Qu, Frederick Nguele Meke, Zheng Zhang, Aaron D. Krabill, Christine S. Muli, Brenson A. Jassim, Jiajun Dong, Quyen D. Nguyen, Yunpeng Bai, Jinyue Li, Yiming Miao, Bardia Asadi, Levi M. Johnson, Jinmin Miao, Darci J. Trader, W. Andy Tao, Zhong‐Yin Zhang   +16 more
wiley   +2 more sources

SARS-CoV-2 NSP14 inhibitor exhibits potent antiviral activity and reverses NSP14-driven host modulation. [PDF]

Nat Commun
Luo M, Mo J, Wang Z, Wei H, Chen K, Shen L, Wang Y, Li L, Chen Y, Chen W, Li X, Feng H, Wang X, Zhou H, Li B, Xu F, Zhao Q, Xu Y, Che J, Zou P, Zhang R, Dong X, Xie W.   +22 more
europepmc   +1 more source

ControlIt: A Universal Framework for Translational, Adaptive, and Online Brain–Computer Interfaces

Advanced Intelligent Systems, EarlyView.
Brain–computer interfaces (BCIs) lack a unified platform that works across signals and algorithms. ControlIt, an open‐source, modular ROS2‐based BCI framework supporting electroencephalography (EEG), electrocorticography (ECoG), and spike‐based decoding across both classification and regression tasks is presented.
Wanlin Yang, Chenyang Li, Xinxiu Xu, Xindong Wang, Yongcheng Guo, Xiaoke Chai, Tianqin Cao, Jiuxiang Song, Nan Wang, Xueming Zhang, Yi Yang, Cong Zheng, He Cui   +12 more
wiley   +1 more source