Results 41 to 50 of about 84,218 (260)

4D Printing of Self‐Immolative Polymers

Advanced Functional Materials, EarlyView.
The integration of self‐immolative polymers (SIPs) into light‐based 3D printed structures is presented as a new “living” 4D printing strategy. By exploiting their metastability and stimuli‐responsiveness, SIP‐containing printed objects can undergo rapid and triggered degrowth under ambient conditions and subsequent regrowth through polymer ...
Johannes Markhart, Philipp Mainik, Pia S. Klee, Eva Blasco   +3 more
wiley   +1 more source

Review of best management practices for aquatic vegetation control in stormwater ponds, wetlands, and lakes [PDF]

, 2013
Auckland Council (AC) is responsible for the development and operation of a stormwater network across the region to avert risks to citizens and the environment.
Champion, Paul, Clayton, John, de Winton, Mary, Edwards, Tracey, Hamilton, David P., Hofstra, Deborah, Jones, Hannah Frances Emily, McBride, Chris G., Rowe, David K., Wells, Rohan, Özkundakci, Deniz   +10 more
core  

Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC

Nature Communications, 2019
Sorafenib is the standard treatment for advanced hepatocellular carcinoma (HCC). However, the development of drug resistance is common. By using genome-wide CRISPR/Cas9 library screening, we identify phosphoglycerate dehydrogenase (PHGDH), the first ...
Lai Wei, Derek Lee, Cheuk-Ting Law, Misty Shuo Zhang, Jialing Shen, Don Wai-Ching Chin, Allen Zhang, Felice Ho‐Ching Tsang, Ceci Lok-Sze Wong, I. Ng, C. C. Wong, Chun‐Ming Wong   +11 more
semanticscholar   +1 more source

In Materia Shaping of Randomness with a Standard Complementary Metal‐Oxide‐Semiconductor Transistor for Task‐Adaptive Entropy Generation

Advanced Functional Materials, EarlyView.
This study establishes a materials‐driven framework for entropy generation within standard CMOS technology. By electrically rebalancing gate‐oxide traps and Si‐channel defects in foundry‐fabricated FDSOI transistors, the work realizes in‐materia control of temporal correlation – achieving task adaptive entropy optimization for reinforcement learning ...
Been Kwak, Ryun‐Han Koo, Youngchan Cho, Changhyeon Han, Dongbin Kim, Soi Jeong, Yunho Shin, Joonhyeok Choi, Jiseong Im, Jonghyun Ko, Jong‐Ho Lee, Jangsaeng Kim, Youngho Kang, Wonjun Shin, Daewoong Kwon   +14 more
wiley   +1 more source

Host stress drives Salmonella recrudescence [PDF]

, 2016
Host stress is well known to result in flare-ups of many bacterial, viral and parasitic infections. The mechanism by which host stress is exploited to increase pathogen loads, is poorly understood.
Bert, Wim, Boyen, Filip, Deforce, Dieter, Dhaenens, Maarten, Favoreel, Herman, Haesebrouck, Freddy, Haesendonck, Roel, Leyman, Bregje, Pasmans, Frank, Shearer, Neil, Thompson, Arthur, Van Parys, Alexander, Verbrugghe, Elin   +12 more
core   +2 more sources

Bio‐Orthogonally Crosslinked Supramolecular Polymer Bottlebrush Hydrogels for Long‐Term 3D Cell Culture

Advanced Functional Materials, EarlyView.
Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi, David Pretzel, Peer Nölte, Kourosh Rezaei, Ulrich S. Schubert, Johannes C. Brendel   +5 more
wiley   +1 more source

Microwave Assisted Synthesis of Py-Im Polyamides [PDF]

, 2012
Microwave synthesis was utilized to rapidly build Py-Im polyamides in high yields and purity using Boc-protection chemistry on Kaiser oxime resin. A representative polyamide targeting the 5′-WGWWCW-3′ (W = A or T) subset of the consensus Androgen and ...
Bacsa B., Baird E. E., Bando T., Baptiste B., Chenoweth D. M., Chenoweth D. M., Chenoweth D. M., Choi J. S., Dale J. A., DeGrado W. F., Dervan P. B., Dervan P. B., Dose C., Edelson B. S., Farnham P. J., Harki D. A., Harris D., James W. Puckett, Joshua T. Green, Kappe C. O., Krutzik P. O., König B., Lai Y.-M., Murray J. K., Muzikar K. A., Nickols N. G., Olenyuk B. Z., Olivos H. J., Palasek S. A., Pelton J. G., Peter B. Dervan, Raskatov J. A., Sinyakov A. N., Su W., Turner J. M., Wade W. S., White S., Wurtz N. R., Xiao J. H.   +38 more
core   +2 more sources

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

Advanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar, Xuen J Ng, Lukas Lechel, Ashish Chand Rajwar, Hendrik Bargel, Abhishek A. Jalan   +5 more
wiley   +1 more source

A putative ATPase mediates RNA transcription and capping in a dsRNA virus. [PDF]

, 2015
mRNA transcription in dsRNA viruses is a highly regulated process but the mechanism of this regulation is not known. Here, by nucleoside triphosphatase (NTPase) assay and comparisons of six high-resolution (2.9-3.1 Å) cryo-electron microscopy structures ...
Jiang, Jiansen, Sun, Jingchen, Yu, Xuekui, Zhou, Z Hong   +3 more
core   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source