Results 71 to 80 of about 120,822 (307)

Impact of Genomic Mutations on the Transcriptional Pathways and Tumor Microenvironment Landscape of Localized Early Prostate Cancer

open access: yesThe Prostate, EarlyView.
ABSTRACT Background The management of intermediate‐risk early prostate cancer (PCa) is challenging due to the difficulty in distinguishing indolent from aggressive tumors. This study explores the association between genomic alterations and the tumor and its microenvironment (TME) and implications for disease progression. Methods We performed multi‐omic
William Lautert‐Dutra   +13 more
wiley   +1 more source

Molecular detection and identification of tick-borne bacteria and protozoans in goats and wild Siberian roe deer (Capreolus pygargus) from Heilongjiang Province, northeastern China

open access: yesParasites & Vectors, 2019
Background Small ruminants are important hosts for various tick species and tick-associated organisms, many of which are zoonotic. The aim of the present study was to determine the presence of tick-borne protozoans and bacteria of public health and ...
Haoning Wang   +5 more
doaj   +1 more source

Information Dynamics and Learning in Complex Adaptive Systems: Toward a Transdisciplinary Framework

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT This article develops a framework for understanding learning and adaptation in complex adaptive systems. Drawing from neuroscience, systems theory, information theory and quantum field theory, it examines how information processing, plasticity and systemic coherence emerge from distributed, nonlinear and feedback‐driven interactions. It argues
Anderson de Souza Sant'Anna
wiley   +1 more source

Implementing a perioperative efficiency initiative for orthopedic surgery instrumentation at an academic center: A comparative before-and-after study. [PDF]

open access: yes, 2019
Optimizing surgical instrumentation may contribute to value-based care, particularly in commonly performed procedures. We report our experience in implementing a perioperative efficiency program in 2 types of orthopedic surgery (primary total-knee ...
Bini, Stefano A   +6 more
core   +1 more source

Ecotoxicological Insights From Ex Vivo Exposure of Whole Blood to PFOS and Glyphosate: Oxidative Stress and Immune Disruption

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study investigated the immunomodulatory effects of PFOS and glyphosate (GLY), both individually and in combination, on the whole blood of three ruminant species (cow, goats, and sheep) exposed ex vivo to environmentally relevant concentrations. The research focused on key biomarkers of oxidative stress (MDA), inflammation (myeloperoxidase
Francesco Molinari   +8 more
wiley   +1 more source

Designing Web-enabled services to provide damage estimation maps caused by natural hazards [PDF]

open access: yes, 2010
The availability of building stock inventory data and demographic information is an important requirement for risk assessment studies when attempting to predict and estimate losses due to natural hazards such as earthquakes, storms, floods or tsunamis ...
Bernabe Poveda, Miguel Angel   +5 more
core   +1 more source

Malnutrition, poor food intake, and adverse healthcare outcomes in non-critically ill obese acute care hospital patients [PDF]

open access: yes, 2018
Obesity, defined as a BMI\ua0≥\ua030\ua0kg/m, has demonstrated protective associations with mortality in some diseases. However, recent evidence demonstrates that poor nutritional status in critically ill obese patients confounds this relationship.
Agarwal, Ekta   +7 more
core   +2 more sources

Dietary shift of the common leopard Panthera pardus in and around Bani Wildlife Sanctuary, western Himalayas: implications for conservation and human–wildlife conflict

open access: yesWildlife Biology, EarlyView.
Understanding the dietary patterns of apex predator like the common leopard Panthera pardus is essential for evaluating their ecological role, particularly in landscapes where human–wildlife conflict is prevalent. In this context, this study investigates the seasonal diet composition of the common leopard in and around the Bani Wildlife Sanctuary, a ...
Iyaz Quyoom   +3 more
wiley   +1 more source

Fritjof Capra’s holism and the structures of philosophical conceptualisation: The logosemantics of complexity

open access: yesKoers : Bulletin for Christian Scholarship, 1998
This article explores a field of study that I call logosemantics: the theory of conceptual structures that determine philosophical expressions of ultimate insight.
P.J. Visagie
doaj   +1 more source

Assessing physiological, behavioral and movement responses to Suprelorin implant delivery methods in free‐ranging eastern grey kangaroos Macropus giganteus

open access: yesWildlife Biology, EarlyView.
Overabundant populations of eastern grey kangaroos Macropus giganteus in peri‐urban areas pose ecological and social challenges. Current management strategies are often hindered by animal welfare and logistical concerns. This study aimed to assess stress responses of kangaroos to two contraceptive delivery methods.
Fabiola R. O. Silva   +4 more
wiley   +1 more source

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