Results 91 to 100 of about 227,059 (331)

Fluorescence Microscopy Assay to Measure HIV-1 Capsid Uncoating Kinetics in vitro

open access: yesBio-Protocol, 2019
The stability of the HIV-1 capsid and the spatiotemporal control of its disassembly, a process called uncoating, need to be finely tuned for infection to proceed.
Chantal Márquez   +6 more
doaj   +1 more source

C-Terminal Amino Acids 471-507 of Avian Hepatitis E Virus Capsid Protein Are Crucial for Binding to Avian and Human Cells. [PDF]

open access: yesPLoS ONE, 2016
The infection of chickens with avian Hepatitis E virus (avian HEV) can be asymptomatic or induces clinical signs characterized by increased mortality and decreased egg production in adult birds.
Xinquan Zhang   +4 more
doaj   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

The role of chikungunya virus capsid-viral RNA interactions in programmed ribosomal frameshifting

open access: yesJournal of Virology
Chikungunya virus (CHIKV) is a globally significant arthropod-borne virus that causes outbreaks in tropical and subtropical regions and is rapidly expanding in geographical range.
Jordan A. Farrington   +2 more
doaj   +1 more source

Protease Cleavage Leads to Formation of Mature Trimer Interface in HIV-1 Capsid [PDF]

open access: yes, 2012
During retrovirus particle maturation, the assembled Gag polyprotein is cleaved by the viral protease into matrix (MA), capsid (CA), and nucleocapsid (NC) proteins.
Angela M. Gronenborn   +10 more
core   +4 more sources

Capsid protein sequence diversity of chicken astrovirus [PDF]

open access: yesAvian Pathology, 2012
The complete capsid gene sequences of 24 chicken astroviruses (CAstVs), collected in the UK, Germany, the Netherlands and South Africa from the 1980s to 2008, were determined and compared with that of a US CAstV (UGA-2006). Pairwise comparisons and phylogenetic analysis demonstrated the existence of two major capsid groups, designated A and B, which ...
V J, Smyth   +4 more
openaire   +2 more sources

Evolutionary Assembly and Future Design of Gibberellin Signaling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gibberellin (GA) signaling is widely regarded as a canonical hormone‐controlled growth pathway, yet accumulating evidence suggests that it emerged through stepwise evolutionary assembly rather than as a pre‐formed regulatory system. Here, we revisit the origin and diversification of the GA pathway from an evolutionary perspective.
Weishu Fan   +4 more
wiley   +1 more source

Influence of amino acid substitutions in capsid proteins of coxsackievirus B5 on free chlorine and thermal inactivation [PDF]

open access: green, 2023
Shotaro Torii   +4 more
openalex   +1 more source

Computer Vision Pipeline for Image Analysis for Freeze‐Fracture Electron Microscopy: Rosette Cellulose Synthase Complexes Case

open access: yesAdvanced Intelligent Discovery, EarlyView.
This paper presents a computer vision (deep learning) pipeline integrating YOLOv8 and YOLOv9 for automated detection, segmentation, and analysis of rosette cellulose synthase complexes in freeze‐fracture electron microscopy images. The study explores curated dataset expansion for model improvement and highlights pipeline accuracy, speed ...
Siri Mudunuri   +6 more
wiley   +1 more source

ICTV Virus Taxonomy Profile: Chrysoviridae [PDF]

open access: yes, 2019
Members of the family Chrysoviridae are isometric, non-enveloped viruses with segmented, linear, dsRNA genomes. There are 3–7 genomic segments, each of which is individually encapsidated.
Castón, José R.   +8 more
core   +2 more sources

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