Results 221 to 230 of about 3,771,869 (289)

Engineering a bivalent nanoparticle vaccine with PCV2 capsid protein and PRRSV epitopes. [PDF]

J Nanobiotechnology
Ma J, Xiao X, Zhou Y, Huang W, Sun J, Chang X, Xiao S, Fang L.   +7 more
europepmc   +1 more source

Engineering Mosaic T7 Bacteriophages for Dual Peptide Display to Enable Cellular Targeting and Ligand‐Directed Protein Capture

Biotechnology Journal, Volume 21, Issue 11, November 2026.
Graphical Abstract and Lay Summary A mosaic T7 phage platform enables simultaneous display of two independent peptides on the same phage particle. The modular design integrates receptor targeting, protein capture, and tissue‐directed in vivo phage display, establishing a versatile methodology for multifunctional phage engineering, receptor ...
Luca Marchetti, Kristina Põšnograjeva, Prakash Lingasamy, Karlis Pleiko, Ivar Ilves, Tambet Teesalu   +5 more
wiley   +1 more source

The Recombinant Viral Capsid Protein rVP1 Induces Protective Immunity Against Coxsackievirus B3 (CVB3) Lethal Challenges in Balb/c Mouse Model. [PDF]

Vaccines (Basel)
Ben M'hadheb M, Hassine IH, Almalki MA, Hassine M, Gharbi J.   +4 more
europepmc   +1 more source

Comparison of Wildtype and Recombinant Adeno‐Associated Virus (AAV) Production Reveals Distinct Productivity and Content Ratio Profiles

Biotechnology Journal, Volume 21, Issue 11, November 2026.
Graphical Abstract and Lay Summary Wildtype and recombinant adeno‐associated virus production are compared across infection, transfection, and hybrid systems in suspension HEK293 cells. Wildtype infection achieves markedly higher vector genome titers and content ratios than triple transfection, and adenoviral helper input governs both packaging ...
Sofia Alfieri, Kelvin H. Lee
wiley   +1 more source

Protection Against Rabbit Hemorrhagic Disease Virus Strains: Efficacy of a New Commercial Recombinant RHDV2 Capsid Protein VP60 Vaccine. [PDF]

Vaccines (Basel)
Fontseca M, Perozo E, Nadal G, Gascón-Torrens S, Montané J, March R, Sitjà M.   +6 more
europepmc   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, Volume 123, Issue 11, Page 3079-3105, November 2026.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source

Elucidation of the binding interaction interface between AAV serotype 11 capsid protein and host nuclear import proteins. [PDF]

Mol Ther Methods Clin Dev
Hoad M, Nematollahzadeh S, Roby JA, Alvisi G, Forwood JK.   +4 more
europepmc   +1 more source

Pathogenic Variants in HEPACAM Alter Protein Localization and Interactome in Astrocytes of the Developing Mouse Cortex

Glia, Volume 74, Issue 11, November 2026.
Pathogenic variants alter hepaCAM protein distribution. Astrocyte‐specific hepaCAM TurboID reveals KCNQ2 as a new interaction partner. Pathogenic variants alter hepaCAM association with key transmembrane proteins. ABSTRACT Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare leukodystrophy characterized by early‐onset macrocephaly,
Robert W. Lewis, Breana C. Dogan, Amy L. Stanek, Elliot B. Evans, Madelyn G. Coble, Hayli E. Spence‐Osorio, Karen L. G. Farizatto, Angie L. Mordant, C. Allie Mills, Laura E. Herring, Katherine T. Baldwin   +10 more
wiley   +1 more source

N-terminal insertion peptides produce varied effects over the cleavage and assembly of norovirus major capsid protein VP1. [PDF]

Virol J
Ma J, Liu J, Huo Y.
europepmc   +1 more source

Productive or Transforming? How Epithelial Compartmentalization of HPV DNA and E6/E7 Transcripts Shapes Cervical Screening Assay Performance

Journal of Medical Virology, Volume 98, Issue 11, November 2026.
ABSTRACT The human papillomavirus (HPV) life cycle is linked to epithelial cell differentiation, with viral genome amplification, E6/E7 transcription, and virion assembly spatially compartmentalized within the cervical epithelium. This organization is disrupted in transforming lesions.
Konstanze Schichl, John Doorbar
wiley   +1 more source