Results 231 to 240 of about 3,771,869 (289)

Development of LC-MS methods for AAV capsid protein quantification and host cell protein profiling. [PDF]

open access: yesMol Ther Methods Clin Dev
Kontogiannis T   +6 more
europepmc   +1 more source

Polyomavirus Drives Cerebellar Lesions in AIDS Monkeys With Ataxia

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Chronic SIV‐infected macaques with ataxia develop severe cerebellar lesions driven by simian polyomavirus 40 (SV40) infection. SV40 preferentially infects cerebellar granule cells, inducing pyroptosis and an aberrant proliferative state. Pyroptotic neuronal injury promotes microglial recruitment and activation, amplifying local neuroinflammation and ...
Tian‐Zhang Song   +9 more
wiley   +1 more source

High-resolution analysis of the human T-cell leukemia virus capsid protein reveals insights into immature particle morphology. [PDF]

open access: yesNat Commun
Arndt WG   +8 more
europepmc   +1 more source

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He   +4 more
wiley   +1 more source

Nuclear trafficking of <i>Anelloviridae</i> capsid protein ORF1 reflects modular evolution of subcellular targeting signals. [PDF]

open access: yesVirus Evol
Petersen GF   +7 more
europepmc   +1 more source

Metabolic Screening and In Silico Investigation of Eucalyptus globulus Essential Oil Bioactives Against DENV‐2 Envelope Protein

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
Network pharmacology and molecular docking identify bioactive compounds from Eucalyptus globulus essential oil with potential activity against dengue virus, highlighting 70 shared targets and DENV‐2‐associated pathways. Globulol and eucalyptol show strong binding to DENV‐2 receptors, with favorable drug‐likeness and toxicity profiles, supporting their ...
Arslan Afzal   +8 more
wiley   +1 more source

Computer-aided drug repurposing & discovery for Hepatitis B capsid protein. [PDF]

open access: yesIn Silico Pharmacol
Mohebbi A   +9 more
europepmc   +1 more source

3dcon: tomogram denoising by deconvolution

open access: yesActa Crystallographica Section D, Volume 82, Issue 11, Page 1240-1250, November 2026.
An open‐source entropy‐regularized deconvolution workflow is presented for denoising tomographic reconstructions from cryo‐electron microscopy.Cryo‐electron tomography is an expanding technology for the study of macromolecules, viruses and cells.
Peter Kirchweger   +3 more
wiley   +1 more source

A nanobiotechnological approach to control non‐persistent aphid‐transmitted plant viruses, based on functionalized virus‐like particles

open access: yesAnnals of Applied Biology, Volume 189, Issue 3, November 2026.
A potyvirus‐derived virus‐like nanoparticle (VLP) interferes in the transmission by aphids of the non‐circulative plant viruses turnip mosaic virus (TuMV, Potyvirus), zucchini yellow mosaic virus (ZYMV, Potyvirus), and cucumber mosaic virus (CMV, Cucumovirus) is also observed. The construct, that consisted of a fusion between a modified TuMV HC‐Pro and
Aranzazu Moreno   +7 more
wiley   +1 more source

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