Results 231 to 240 of about 3,771,869 (289)
Development of LC-MS methods for AAV capsid protein quantification and host cell protein profiling. [PDF]
Kontogiannis T +6 more
europepmc +1 more source
Polyomavirus Drives Cerebellar Lesions in AIDS Monkeys With Ataxia
Chronic SIV‐infected macaques with ataxia develop severe cerebellar lesions driven by simian polyomavirus 40 (SV40) infection. SV40 preferentially infects cerebellar granule cells, inducing pyroptosis and an aberrant proliferative state. Pyroptotic neuronal injury promotes microglial recruitment and activation, amplifying local neuroinflammation and ...
Tian‐Zhang Song +9 more
wiley +1 more source
High-resolution analysis of the human T-cell leukemia virus capsid protein reveals insights into immature particle morphology. [PDF]
Arndt WG +8 more
europepmc +1 more source
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He +4 more
wiley +1 more source
Nuclear trafficking of <i>Anelloviridae</i> capsid protein ORF1 reflects modular evolution of subcellular targeting signals. [PDF]
Petersen GF +7 more
europepmc +1 more source
Network pharmacology and molecular docking identify bioactive compounds from Eucalyptus globulus essential oil with potential activity against dengue virus, highlighting 70 shared targets and DENV‐2‐associated pathways. Globulol and eucalyptol show strong binding to DENV‐2 receptors, with favorable drug‐likeness and toxicity profiles, supporting their ...
Arslan Afzal +8 more
wiley +1 more source
Computer-aided drug repurposing & discovery for Hepatitis B capsid protein. [PDF]
Mohebbi A +9 more
europepmc +1 more source
3dcon: tomogram denoising by deconvolution
An open‐source entropy‐regularized deconvolution workflow is presented for denoising tomographic reconstructions from cryo‐electron microscopy.Cryo‐electron tomography is an expanding technology for the study of macromolecules, viruses and cells.
Peter Kirchweger +3 more
wiley +1 more source
New Advances in Anti-HIV-1 Strategies Targeting the Assembly and Stability of Capsid Protein. [PDF]
Zhang C, Li B, Li J, Zhang H, Wu Y.
europepmc +1 more source
A potyvirus‐derived virus‐like nanoparticle (VLP) interferes in the transmission by aphids of the non‐circulative plant viruses turnip mosaic virus (TuMV, Potyvirus), zucchini yellow mosaic virus (ZYMV, Potyvirus), and cucumber mosaic virus (CMV, Cucumovirus) is also observed. The construct, that consisted of a fusion between a modified TuMV HC‐Pro and
Aranzazu Moreno +7 more
wiley +1 more source

