Results 231 to 240 of about 227,059 (331)

Mini‐Catalytically Inactive Cas13X‐Derived RNA Base Editing of β‐Catenin Attenuates Pulmonary Damage in a Murine Acute Lung Injury Model

open access: yesMedComm, Volume 7, Issue 4, April 2026.
AAV6.2FF‐delivered CARTEL (mini‐dCas13X‐mediated A‐to‐I editor) introduces c.121A>G editing in β‐catenin RNA of alveolar type II cells, leading to sustained Wnt/β‐catenin activation, robust AT2 proliferation, significant attenuation of LPS‐induced acute lung injury, and no excess off‐target edits or fibrotic toxicity for 4 weeks.
Wenyi Liu   +13 more
wiley   +1 more source

Characterization of high affinity IgM and IgG monoclonal antibodies against norovirus variants GII.4 and GII.17

open access: yesProtein Science, Volume 35, Issue 4, April 2026.
Abstract Human noroviruses are a leading cause of acute gastroenteritis worldwide, yet the molecular principles governing antibody recognition of their highly repetitive capsid remain poorly understood. Here, we immunized mice with virus‐like particles (VLPs) from the pandemic GII.4 strain and the emergent GII.17 strain, generating monoclonal IgM and ...
Jumpei Tagawa   +10 more
wiley   +1 more source

Genome-wide Associations of Flavivirus Capsid Proteins [PDF]

open access: green, 2019
Priscilla Li Shan Boon   +9 more
openalex   +1 more source

Breeding cold‐tolerant Orius laevigatus lines improves thermal tolerance and body size: implications for biological control

open access: yesPest Management Science, Volume 82, Issue 4, Page 3011-3018, April 2026.
Biological control agents performance is influenced by temperature. Two cold‐tolerant lines of O. loevigatus were developed, improving their fitness at both low and high temperatures, offering advantages far augmentative biological control. Abstract BACKGROUND The performance of biological control agents (BCAs) is strongly influenced by environmental ...
Ana Belén Abelaira   +4 more
wiley   +1 more source

Predictive value of gB2 antibodies for maternal–fetal transmission after primary cytomegalovirus infection treated with valacyclovir

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 4, Page 455-460, April 2026.
ABSTRACT Objective To estimate the residual risk of maternal–fetal transmission after primary cytomegalovirus (CMV) infection in the periconceptional period or the first trimester in women treated with valacyclovir, and to assess whether the presence of glycoprotein B2 (gB2)‐specific immunoglobulin (Ig)‐G antibodies on immunoblot analysis refines fetal
K. O. Kagan   +6 more
wiley   +1 more source

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