Results 251 to 260 of about 227,059 (331)
ABSTRACT Autophagy and the ubiquitin/26S proteasome system (UPS) play critical roles in the immune defence of the host against pathogen invasion. As a countermeasure, pathogens deploy effector proteins to subvert or hijack autophagy and UPS processes.
Yaqian Shi +7 more
wiley +1 more source
New Advances in Anti-HIV-1 Strategies Targeting the Assembly and Stability of Capsid Protein. [PDF]
Zhang C, Li B, Li J, Zhang H, Wu Y.
europepmc +1 more source
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling +9 more
wiley +1 more source
Heat shock induces Arc/Arg3.1 Cys34‐Cys159 disulfide crosslinking, promoting oligomerization and Hsp70‐CHIP‐dependent ubiquitination followed by proteasomal degradation during recovery. Disrupting disulfide formation (C159A) impairs CHIP‐mediated ubiquitination and stabilizes Arc/Arg3.1, whereas HSF1 loss limits inducible Hsp70 and leads to Arc ...
Dami So +7 more
wiley +1 more source
Computer-aided drug repurposing & discovery for Hepatitis B capsid protein. [PDF]
Mohebbi A +9 more
europepmc +1 more source

