Results 151 to 160 of about 29,311 (260)

Pathway-Capsule Neural Networks

open access: yesResearch and Development on Information and Communication Technology
The progress made in Next-Generation Sequencing technology has resulted in many genetic databases, which offer the potential for more effective diagnostic tools. Recent literature highlights Artificial Intelligence (AI) as one of the most potent methods.
openaire   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang   +13 more
wiley   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao   +8 more
wiley   +1 more source

Interconnected Porous Hydrogels with Tunable Anisotropy Through Aqueous Emulsion Bioprinting

open access: yesAdvanced Functional Materials, EarlyView.
A 3D bioprintable microporous bioink is developed using an aqueous two‐phase system (ATPS) composed of extracellular matrix (ECM) mimetic biopolymers. The ATPS bioink enables the fabrication of interconnected porous architectures with up to 70% porosity, supporting long‐term cell viability and 3D cell alignment, enabling a simultaneous generation of ...
Hugo Edgar‐Vilar   +4 more
wiley   +1 more source

Robust and Reversible Thermofluorescence in Solvent‐Free Thermoplastic Polyurethane Composites

open access: yesAdvanced Functional Materials, EarlyView.
Thermofluorescent polymer composites with high‐contrast optical outputs are prepared by solvent‐free blending of indenoquinacridone dye into a thermoplastic polyurethane matrix. The temperature‐dependent fluorescence originates from aggregation–dissociation of the dye molecules, regulated by competing hydrogen bonds from the polymer matrix.
Guanghua Yu   +8 more
wiley   +1 more source

Controlled Movement of Soft Actuators using Multi‐Responsive Microgel Arrays and Microcirculatory Systems

open access: yesAdvanced Functional Materials, EarlyView.
Microscale hydrogels (microgels) feature improved mass transport characteristics supportive of fast actuation and chemical tunability amenable to programmed stimuli response. A unique soft actuator architecture is realized by encapsulating microgels in soft microcirculatory systems which enable the convenient delivery of liquid stimuli for powering and
Nengjian Huang   +2 more
wiley   +1 more source

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