Results 71 to 80 of about 5,317,982 (276)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
WAGE PATTERN AND COMPOSITION OF PURSE SEINE SHIP CREW: CASE STUDY OF KM. SUMBER MAJU
Jurnal Teknologi Perikanan dan KelautanThe purse seine used in Batam City is a type of waring, known as a purse seine waring. Each crew member's income has a different share depending on the amount of catch and the position level on the ship. Calculation of the profit-sharing system for purse
Suci Asrina Ikhsan +4 more
doaj +1 more source
Non-Statistical Effects in Neutron Capture
, 2008 There have been many reports of non-statistical effects in neutron-capture measurements. However, reports of deviations of reduced-neutron-width distributions from the expected Porter-Thomas (PT) shape largely have been ignored.
Andreas Zilges +14 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Rangifer, 1995 Seventeen free-ranging moose {Alces alces) (2 adult males, 13 adult females and 2 female calves) were immobilized with a combination of medetomidine hydochloride (MED) and ketamine hydrochloride (KET) in early autumn (August-September).
Jon M. Arnemo
doaj +1 more source
Resonant capture by inward migrating planets
, 2000 We investigate resonant capture of small bodies by planets that migrate inwards, using analytic arguments and three-body integrations. If the orbits of the planet and the small body are initially circular and coplanar, the small body is captured when it ...
Goldreich P. +3 more
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 2023 Deep Learning (DL) model sizes are increasing at a rapid pace, as larger models typically offer better statistical performance. Modern Large Language Models (LLMs) and image processing models contain billions of trainable parameters. Training such massive neural networks incurs significant memory requirements and financial cost.
Ilka Heinze, Thomas Henschel, Jens Hirt
openaire +3 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source