Results 81 to 90 of about 2,265,093 (319)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Prevalence and Characteristics of Individuals with Preserved Ratio Impaired Spirometry (PRISm) and/or Impaired Lung Function in Japan: The OCEAN Study

open access: yesInternational Journal of COPD, 2021
Toshihiko Kaise,1 Eishin Sakihara,2 Kentaro Tamaki,3 Hiroaki Miyata,4 Norimichi Hirahara,4 Oksana Kirichek,5 Ryosuke Tawara,1 Shoko Akiyama,1 Masayuki Katsumata,1 Mei Haruya,6 Takeo Ishii,7 Edgar P Simard,8 Bruce E Miller,8 Ruth Tal-Singer8 1Japan ...
Kaise T   +13 more
doaj  

ALAT TANGKAP BURUNG YANG DIGUNAKAN PENDUDUK DI RAWA KECAMATAN DANAU PANGGANG, KABUPATEN HULU SUNGAI UTARA (Bird Capture Devices Used by Community at Swamp of Danau Panggang District, Hulu Sungai Utara Regency)

open access: yesJurnal Manusia dan Lingkungan, 2013
ABSTRAK Beragam alat digunakan untuk menangkap burung air yang berpotensi ekonomi bagi sebagian penduduk Kecamatan Danau Panggang, Kabupaten Hulu Sungai Utara.
Noraini Noraini   +2 more
doaj   +1 more source

SEASIDE CAPTURES [PDF]

open access: yesThe Canadian Entomologist, 1885
I visited Fire Island, Rockaway Beach, Long Beach and Coney Island during the seasons of 1883 and 1884. Found myriads of Cicindela hirticollis and dorsalis, Say. The beaches were fairly alive with these beetles. The hirticollis were most abundant in the latter part of June and early part of July, and dorsalis at the end of July and beginning of August.
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Participatory processes for public lands: Do provinces practice what they preach?

open access: yesEcology and Society, 2017
Here, we analyze the current spaces for public participation in Crown (public) land management through a comparative study that focuses on the Canadian provinces of New Brunswick and Nova Scotia. We define spaces for public participation as opportunities
Lauren F. Miller, Solange Nadeau
doaj   +1 more source

Attention capture by multiple events using dynamic displays [PDF]

open access: yes
Being able to select relevant visual information from among irrelevant information is critical for the successful accomplishment of many day to day activities. However, the locus of attentional selection is not always under the control of the observer.
Sunny, Meera Mary
core  

Constraint capture and maintenance in engineering design [PDF]

open access: yes, 2008
The Designers' Workbench is a system, developed by the Advanced Knowledge Technologies (AKT) consortium to support designers in large organizations, such as Rolls-Royce, to ensure that the design is consistent with the specification for the particular ...
Knott, D.   +7 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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