Results 101 to 110 of about 2,725,707 (298)
The International Law Commission’s Conclusions on the identification of customary international law show that contemporary international law grant a modest role to international organisations as independent actors in the formation of customary international law, which is remarkable, given that organisations participate ever more fully in international ...
openaire +3 more sources
The objective of this work was describe the acarologic fauna (Order: Ixodida) in the municipality of Bom Jesus dos Perdões, beyond compare two capture methods at different points and collection times.
Yuri Ferreira Vicentini +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A Diagnosis of Daily News’ Framing of Anti-Mnangagwa Protests Through the Media Capture Lens
This qualitative interpretive case study investigates how Zimbabwe’s independent daily newspaper, the Daily News, reported on the 31 March 2025, anti-President Emmerson Mnangagwa protests organized by war veterans.
Takunda Maodza
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Covalent organic frameworks (COFs) have emerged as promising materials for the capture and photoluminescent detection of pharmaceutical contaminants in aquatic environments due to their tunable porosity, high surface area, and structural versatility ...
Johana Herrero +3 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Il y a longtemps que les theories de John F. McLennan, maintenant considerees demodees, ont ete refutees. L'ethnologie moderne a produit depuis, des analyses de plus en plus sophistiquees qu'il est pertinent de rapporter aux idees de cet auteur. Un echantillonage d'exemples ethnographiques provenant d'Indonesie, des Caraibes, d'Amazonie, Australie et ...
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