Results 121 to 130 of about 2,725,707 (298)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
The Use of Mixture Models in Capture-Recapture [PDF]
, 2015 Mixture models have been widely used to model heterogeneity. In this thesis, we focus on the use of mixture models in capture--recapture, for both closed populations and open populations. We provide both practical and theoretical investigations.
Yu, Chen
core
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Advances in Downstream Processing of Monoclonal Antibodies
AntibodiesAlthough mAbs have great therapeutic potential, their use in medicine is currently limited by the high cost of their manufacturing. Significant developments in upstream processing technologies have caused downstream processing (DSP) to become the ...
Michał Kołodziej, Dorota Antos
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Elite Capture or Capture Elites? Lessons from the ‘Counter-elite’ and ‘Co-opt-elite’ Approaches in Bangladesh and Ghana [PDF]
Community-based development has been criticized for its inadequate understanding of power relationships at the local level, which thus leaves room for elite capture.
Wong, Sam
core
WAGE PATTERN AND COMPOSITION OF PURSE SEINE SHIP CREW: CASE STUDY OF KM. SUMBER MAJU
Jurnal Teknologi Perikanan dan KelautanThe purse seine used in Batam City is a type of waring, known as a purse seine waring. Each crew member's income has a different share depending on the amount of catch and the position level on the ship. Calculation of the profit-sharing system for purse
Suci Asrina Ikhsan +4 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
CO2 Highways for Europe: Modeling a Carbon Capture, Transport and Storage Infrastructure for Europe [PDF]
We present a mixed integer, multi-period, cost-minimizing carbon capture, transport and storage (CCTS) network model for Europe. The model incorporates endogenous decisions about carbon capture, pipeline and storage investments; capture, flow and ...
Johannes Herold +3 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source