Results 171 to 180 of about 14,957,077 (381)

Spectrally Tunable 2D Material‐Based Infrared Photodetectors for Intelligent Optoelectronics

Advanced Functional Materials, EarlyView.
Intelligent optoelectronics through spectral engineering of 2D material‐based infrared photodetectors. Abstract The evolution of intelligent optoelectronic systems is driven by artificial intelligence (AI). However, their practical realization hinges on the ability to dynamically capture and process optical signals across a broad infrared (IR) spectrum.
Junheon Ha, Yingshan Ma, Yong Nam An, Sung‐Un An, Hyeon Hak Jung, Suvi‐Tuuli Varjamo, Jiwon Yoo, Junho Min, Hanvit Kim, Faisal Ahmed, Sang Hoon Chae, Young Min Song, Weiwei Cai, Tawfique Hasan, Zhipei Sun, Dong‐Ho Kang, Hyeon‐Jin Shin, Yunyun Dai, Hoon Hahn Yoon   +18 more
wiley   +1 more source

CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients.

Journal of Clinical Investigation, 2016
C. Turtle, L. Hanafi, C. Berger, T. Gooley, S. Cherian, M. Hudecek, D. Sommermeyer, Katherine Melville, B. Pender, Tanya M Budiarto, E. Robinson, Natalia N Steevens, Colette N. Chaney, L. Soma, Xueyan Chen, C. Yeung, B. Wood, Daniel H. Li, Jianhong Cao, S. Heimfeld, M. Jensen, S. Riddell, D. Maloney   +22 more
semanticscholar   +1 more source

CD19-CAR T-cell therapy induces deep tissue depletion of B cells

Annals of the Rheumatic Diseases
Objectives CD19-targeting chimeric antigen receptor (CAR) T-cell therapy can induce long-term drug-free remission in patients with autoimmune diseases (AIDs). The efficacy of CD19-CAR T-cell therapy is presumably based on deep tissue depletion of B cells;
Carlo Tur, Markus Eckstein, Joachim Velden, S. Rauber, Christina Bergmann, J. Auth, Laura Bucci, G. Corte, Melanie Hagen, A. Wirsching, Ricardo Grieshaber-Bouyer, Petra Reis, Nicolai Kittan, J. Wacker, Aleix Rius Rigau, A. Ramming, Maria-Antonietta D’Agostino, Arndt Hartmann, Fabian Müller, A. Mackensen, A. Bozec, G. Schett, M. Raimondo   +22 more
semanticscholar   +1 more source

Nephrotoxicity in CAR-T Cell Therapy

Transplantation and Cellular Therapy
Chimeric antigen receptor (CAR)-T cell therapy is a novel therapy for the treatment of different hematologic malignancies. Besides its efficiency, CAR-T cell therapy is associated with significant toxicity, primarily manifested as cytokine release syndrome (CRS) and neurotoxicity.
Karol Sadowski, Weronika Ploch, Alicja Downar, Wiktoria Giza, Dorota Szcześ, Wioletta Olejarz, Wiesław W. Jędrzejczak, Jolanta Małyszko, Grzegorz Basak   +8 more
openaire   +2 more sources

Digital Discovery of Synthesizable Metal−Organic Frameworks via Molecular Dynamics‑Informed, High‑Fidelity Deep Learning

Advanced Functional Materials, EarlyView.
Tabular foundation model interrogates the synthetic likelihood of metal−organic frameworks. Abstract Metal–organic frameworks (MOFs) are celebrated for their chemical and structural versatility, and in‑silico screening has significantly accelerated their discovery; yet most hypothetical MOFs (hMOFs) never reach the bench because their synthetic ...
Xiaoyu Wu, Rui Zheng, Quan Liu, Jianwen Jiang   +3 more
wiley   +1 more source

Factors Influencing the Propensity to Make Long Distance Trips by Rail [PDF]

, 1986
This paper discusses sane of the major results of the inter-urban rail trip generation models developed during the studentship of J M Rickard under the supervision of Drs C A Nash and A S Fowkes.
Nash, C.A., Rickard, J.M.
core  

From Waste to Value: Conversion of Calcium Sulfate to Vaterite via Carbon Capture and Storage

Advanced Functional Materials, EarlyView.
This study introduces a new concept for carbon management that relies on the carbonation of industrial gypsum waste and yields phase‐pure vaterite at ambient conditions without any additives. The obtained vaterite is further shown to be a reactive material that develops compressive strength in aqueous suspensions like conventional cements.
Carlos Pimentel, German Montes‐Hernández, Pablo Almarza‐Cifuentes, Matthias Kellermeier, Alexander E.S. Van Driessche   +4 more
wiley   +1 more source

CAR T cells and T cells phenotype and function are impacted by glucocorticoid exposure with different magnitude

Journal of Translational Medicine
Background Chimeric antigen receptor (CAR) T cell therapy is associated with high risk of adverse events. Glucocorticoids (GCs) are cornerstone in the management of high-grade cytokine release syndrome (CRS) and immune effector cell-associated ...
Thomas Poiret, Sara Vikberg, Esther Schoutrop, Jonas Mattsson, Isabelle Magalhaes   +4 more
doaj   +1 more source

A chimeric antigen receptor-based cellular safeguard mechanism for selective in vivo depletion of engineered T cells

Frontiers in Immunology
Adoptive immunotherapy based on chimeric antigen receptor (CAR)-engineered T cells has exhibited impressive clinical efficacy in treating B-cell malignancies.
Mortimer Svec, Sarah Dötsch, Linda Warmuth, Manuel Trebo, Simon Fräßle, Stanley R. Riddell, Ulrich Jäger, Elvira D’Ippolito, Dirk H. Busch   +8 more
doaj   +1 more source

Viscoelasticity‐Induced Controllable Periodic Meso‐Textures of Liquid Crystal Polymers in Additive Manufacturing

Advanced Functional Materials, EarlyView.
Viscoelasticity‐driven instabilities are harnessed to create tunable, periodic textures in 3D‐printed liquid crystalline polymers. This study illustrates how processing parameters control these spontaneous meso‐scale patterns. These unique structural architectures unlock new possibilities for functional devices, ranging from photonic components to ...
Miaomiao Zou, Jiongyi Yan, Dick F. Firdaus, Amy Jin, Jiaxuan Li, Shushan Wang, Ran Chen, Xudong Tao, Zehao Ji, Yi Liu, Zichen Wang, Christos Margadji, Mark Kotter, J. Axel Zeitler, George G. Malliaras, Ronan Daly, Andrew Gleadall, Sebastian W. Pattinson   +17 more
wiley   +1 more source