Results 201 to 210 of about 14,957,077 (381)

RBIO-06. COMBINING FLASH RADIOTHERAPY WITH GD2-CAR T CELL IMMUNOTHERAPY IN DIFFUSE INTRINSIC PONTINE GLIOMA [PDF]

, 2023
Haille E. Soderholm, Zara Kiger, Wonju Kim, Robbie G. Majzner, Bonnie Lau   +4 more
openalex   +1 more source

CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade

Nature Medicine, 2018
Theodoros Giavridis, Sjoukje J. C. van der Stegen, Justin Eyquem, Mohamad Hamieh, A. Piersigilli, M. Sadelain   +5 more
semanticscholar   +1 more source

Novel 3D‐Printed Biophotonic Scaffold Displaying Luminescence under Near‐Infrared Light for Photopharmacological Activation and Biological Signaling Compound Release

Advanced Healthcare Materials, EarlyView.
Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati, Ekin Opar, Virginia Alessandra Gobbo, Carlo Matera, Fabio Riefolo, Rossella Castagna, Julien Colombelli, Andrew Draganski, Joshua Baggott, Mika Lastusaari, Pau Gorostiza, Laeticia Petit, Jonathan Massera   +12 more
wiley   +1 more source

Assessment of chimeric antigen receptor T (CAR-T) cytotoxicity by droplet microfluidics in vitro [PDF]

, 2021
Kuan Un Wong, Jingxuan Shi, Peng Li, Haitao Wang, Yanwei Jia, Chu‐Xia Deng, Lianmei Jang, Ada Hang‐Heng Wong   +7 more
openalex   +1 more source

Increased Anti‐Psoriatic Effect of Anti‐Inflammatory Dendrimers Using Fluid Catanionic Vesicle‐Based Topical Formulations

Advanced Healthcare Materials, EarlyView.
Next‐Generation Psoriasis Therapy – With advanced dendrimer‐based formulations, this study paves the way for highly effective, skin‐permeable treatments. Encapsulated in fluid catanionic vesicles, IMD‐006 and its analogues show promising anti‐psoriatic effects offering a targeted, non‐invasive approach to managing chronic skin inflammation.
Ranime Jebbawi, Abdelouahd Oukhrib, Emily Clement, Hélène Labie, Stéphanie Cassel, Séverine Fruchon, Anne‐Marie Caminade, Michel Simon, Rémy Poupot, Cédric‐Olivier Turrin, Muriel Blanzat   +10 more
wiley   +1 more source

Supplementary table 6 from Single-Cell Transcriptomics Reveals Immune Reconstitution in R/R T-ALL/LBL Patients with Donor-Derived CD7 CAR-T Therapy

, 2023
Wei Chen, Hui Shi, Zhuojun Liu, Fan Yang, Jia Liu, Leqiang Zhang, Yajin Wu, Yuanshi Xia, Yuxuan Ou, Ruiting Li, Ting Zhang, Jiecheng Zhang, Xiaoyan Ke, Kai Hu, Jian Yu   +14 more
openalex   +1 more source

239 CSPG4-targeted CAR T cells demonstrate potent antitumor activity in an orthotopic murine model of anaplastic thyroid cancer [PDF]

, 2023
Giulia Cattaneo, Marco Ventin, Venkata R. Vantaku, Shahrzad Arya, Jingyu Jia, Luke Maggs, Xinhui Wang, Sareh Parangi, Cristina R. Ferrone, Soldano Ferrone   +9 more
openalex   +1 more source

IL‐2 Free Expansion of T Cells with Immunofilaments

Advanced Healthcare Materials, EarlyView.
Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck, Lea Weiss, René Classens, Carl G. Figdor, Roel Hammink   +4 more
wiley   +1 more source

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Effectiveness of CAR-T treatment toward the potential risk of second malignancies

Frontiers in Immunology
Massimo Martino, Massimo Martino, Gaetana Porto, Gaetana Porto, Giorgia Policastro, Giorgia Policastro, Caterina Alati, Caterina Alati, Barbara Loteta, Barbara Loteta, Maria Caterina Micó, Maria Caterina Micó, Clizia Argiró, Clizia Argiró, Maria Altomonte, Maria Altomonte, Tiziana Moscato, Tiziana Moscato, Demetrio Labate, Demetrio Labate, Vincenzo Dattola, Vincenzo Dattola, Carmelo Massimiliano Rao, Carmelo Massimiliano Rao, Francesca Cogliandro, Francesca Cogliandro, Filippo Antonio Canale, Filippo Antonio Canale, Virginia Naso, Virginia Naso, Gianfranco Filippelli, Antonino Iaria, Martina Pitea, Martina Pitea   +33 more
doaj   +1 more source