Results 31 to 40 of about 172,432 (312)
, 2022 S.53-66Prof. Westkämper gives an overview of current activities in Fraunhofer institutes concerning latest techniques and technologies in the field of car-body ...
Westkämper, Engelbert
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, 2022 28 FolienAn important trend in car body construction of the automobile industry is still the lightweight construction.. Aluminum materials have a strategic importance for this.
Puschmann, Markus +2 more
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Investigation of relationship between drag and lift coefficients for a generic car model [PDF]
, 2014 The paper presents a study of aerodynamic characteristics of a car, which has the simplified geometric shape, so called Ahmed body. Flow around the body and the influence of its rear slant angle on drag are widely studied by numerous researchers. However,
MASSOUH, Fawaz, DOBREV, Ivan
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Evaluation of braze welded joints using the ultrasonic method
Open EngineeringBrazed welded joints are increasingly used in the construction of motor vehicle bodies due to the fact that in the process of their manufacture, there is no damage to the zinc coating that protects the body sheet from corrosion. The main objective of the
Ulbrich Dariusz +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Subject-specific body segment parameters' estimation using biplanar X-rays: a feasibility study [PDF]
, 2010 In order to improve the reliability of children's models, the aim of this study was to determine the subject-specific masses and 3D locations of the centres of mass (CoM) of body segments using biplanar X-rays.
Sébastien Laporte +7 more
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