Results 71 to 80 of about 24,885 (307)

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal   +3 more
wiley   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

open access: yesAdvanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu   +18 more
wiley   +1 more source

Dépendance à la voiture et précarité à Bruxelles

open access: yesBrussels Studies
In this article, we address the intersecting issues of deprivation and car dependency in the Brussels Region by analysing the car ownership of households through the prism of their level of deprivation.
Mathias De Meyer, Jessica Gilsoul
doaj   +1 more source

Economic development and changes in car ownership patterns. [PDF]

open access: yes
The contributions of this paper are twofold: On the one hand, the paper analyses the factors determining the growth in car ownership in Spain over the last two decades, and, on the other, the paper provides empirical evidence for a controversial ...
Josep Lluís Raymond, Anna Matas
core  

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

open access: yesAdvanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong   +7 more
wiley   +1 more source

Autoafhankelijkheid en kansarmoede in Brussel

open access: yesBrussels Studies
In this article, we address the intersecting issues of deprivation and car dependency in the Brussels Region by analysing the car ownership of households through the prism of their level of deprivation.
Mathias De Meyer, Jessica Gilsoul
doaj   +1 more source

Volatility of car ownership, commutingmode and time in the UK

open access: yes, 2004
This paper has two objectives: to examine the volatility of travel behaviour over timeand consider the factors explaining this volatility; and to estimate the factors determiningcar ownership and commuting by car. The analysis is based on observations of
Hanly, M, Dargay, J
core  

3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species

open access: yesAdvanced Science, EarlyView.
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu   +11 more
wiley   +1 more source

Car dependency and precariousness in Brussels

open access: yesBrussels Studies
In this article, we address the intersecting issues of deprivation and car dependency in the Brussels Region by analysing the car ownership of households through the prism of their level of deprivation.
Mathias De Meyer, Jessica Gilsoul
doaj   +1 more source

Mobility tools and use: Accessibility’s role in Switzerland

open access: yesJournal of Transport and Land Use, 2018
In much of Switzerland, public transport offers high levels of accessibility to workplaces and other places that make season tickets legitimate substitutes for a car. These similar patterns of accessibility provided by both modes result in high levels of
Allister Loder, Kay Werner Axhausen
doaj   +1 more source

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