Results 81 to 90 of about 63,125 (274)

Therapeutic advances in pruritus as a model of personalized medicine

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Recent advances in itch biology reveal that chronic pruritus arises from distinct neuroimmune pathways driven by cytokines, JAK, BTK and GPCRs. Targeted biologics and small molecule inhibitors such as dupilumab, nemolizumab, remibrutinib and JAK inhibitors precisely modulate these pathways, leading to a new era of personalized therapeutics in pruritus.
Kelsey Auyeung, Ramsey Kubofcik, Brian S. Kim   +2 more
wiley   +1 more source

Impact of nitrogen fertilization on raspberry (Rubus idaeus L.) fruit quality and soil fertility

Notulae Botanicae Horti Agrobotanici Cluj-Napoca
This study investigates the effects of nitrogen fertilization on raspberry fruit quality and soil fertility over two years. The experiment involved the application of complex NPK fertilizers and varying doses of nitrogen fertilizer (CAN) to raspberry ...
Ljiljana BOŠKOVIĆ-RAKOČEVIĆ, Ivan GLIŠIĆ, Ivana RADOVANOVIĆ, Gorica PAUNOVIĆ, Jelena MLADENOVIĆ, Mira MILINKOVIĆ, Radmila ILIĆ   +6 more
doaj   +1 more source

Analisis Tata Cara Pemotongan, Penyetoran, Dan Pelaporan Pajak Penghasilan Pasal 23 Atas Jasa Konsultan Pada Pt Telkom Indonesia, Tbk Sesuai Dengan Peraturan Undang-Undang Nomor 36 Tahun 2008

, 2023
Riani Tanjung, Tsaniya Faza Damayanti
openalex   +2 more sources

The SWITCH algorithm: An expert consensus on treat‐to‐target criteria for chronic prurigo

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The SWITCH project assessed patients' most distressing symptoms and therapy goals, followed by an expert‐based consensus procedure to define T2T criteria for patients with chronic prurigo (CPG)/prurigo nodularis. Based on these validated criteria, a 4‐step SWITCH algorithm was established to enhance CPG therapy outcomes and reduce patient burden ...
Lea S. Stahl, Claudia Zeidler, Joyce Loewenthal, Svenja Royeck, Matthias Augustin, Robert Bissonnette, Sarina Elmariah, Brian S. Kim, Laurent Misery, Hiroyuki Murota, Hong Liang Tey, Elke Weisshaar, Gil Yosipovitch, Franz J. Legat, Adam Reich, Martin Metz, Sonja Ständer   +16 more
wiley   +1 more source

Synthesis, Crystallographic Study and Antibacterial Activity of Ternary Copper(II) Complex with Chromone-Based Ligand and Pyridine

Crystals
A new copper(II) complex was synthesized using chromone-2-carboxylic acid as the main ligand, and coordinated pyridine molecules. The complex was successfully crystallized and structurally characterized by single crystal X-ray diffraction.
Nikolina Filipović, Anamarija Stanković, Martina Medvidović-Kosanović, Dominik Goman, Stjepan Šarić, Goran Palijan, Tomislav Balić   +6 more
doaj   +1 more source

Aprendiendo FOL : cara a cara

, 2016
ESP
openaire   +2 more sources

Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The current study found no evidence of cumulative increased safety risks with upadacitinib 15 or 30 mg for up to 6 years and over 9000 patient‐years of safety data in adults and adolescents. There were low rates of adjudicated major adverse cardiovascular events, adjudicated thromboembolic events and malignancies. Abstract Background Atopic dermatitis (
Christopher G. Bunick, Alan D. Irvine, Jonathan I. Silverberg, Emma Guttman‐Yassky, Mona Shahriari, Xinghua Gao, Stephan Weidinger, Norito Katoh, Namita Vigna, Deanne M. Dilley, Elvira D'Andrea, Henrique D. Teixeira, Andrew M. Platt, Gweneth F. Levy   +13 more
wiley   +1 more source

Divergence analysis of Cucurbita pepo L. population for seed oil production

Notulae Botanicae Horti Agrobotanici Cluj-Napoca
The work aim was to analyze the divergence of the genotypes of common pumpkin (Cucurbita pepo L.) and to select suitable parents for the breeding program to increase the production of cold-pressed oil.
Dalibor TOMIĆ, Mirjana RADOVANOVIĆ, Miloš MARJANOVIĆ, Vesna ĐUROVIĆ, Vladeta STEVOVIĆ, Nenad PAVLOVIĆ, Đorđe LAZAREVIĆ, Vladimir ZORNIĆ, Milomirka MADIĆ   +8 more
doaj   +1 more source

Rapid improvement of itch with nemolizumab in atopic dermatitis and prurigo nodularis phase 3 studies

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Achieving rapid control of itch in atopic dermatitis and prurigo nodularis may minimize symptomatology and disease burden. Analysis of clinical trials in atopic dermatitis and prurigo nodularis showed significantly more patients in nemolizumab versus placebo groups achieved a meaningful clinical response in itch within 48 h, and separation increased ...
Sonja Ständer, Sarina B. Elmariah, Shawn G. Kwatra, Gil Yosipovitch, Andrew E. Pink, Soo Yeon Cheong, Xiaoxiao Chen, Zarif K. Jabbar‐Lopez, Liliana Ulianov, Christophe Piketty, Jonathan I. Silverberg   +10 more
wiley   +1 more source

Valorization of Sour Cherry Kernels: Extraction of Polyphenols Using Natural Deep Eutectic Solvents (NADESs)

Molecules
The objective of this research was to optimize the natural deep eutectic solvent (NADES) extraction process from sour cherry kernels (Prunus cerasus L.).
Danica Božović, Ivana Dimić, Nemanja Teslić, Aleksandra Mišan, Milica Pojić, Alena Stupar, Anamarija Mandić, Sanja Milošević, Zoran Zeković, Branimir Pavlić   +9 more
doaj   +1 more source