Results 171 to 180 of about 28,706 (230)
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Archives of Ophthalmology, 1968
Carbachol in a weak dilution (0.01%) is effective and relatively nonirritating when used as a miotic after the lens is removed in round pupil cataract extraction.
H, Beasley +3 more
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Carbachol in a weak dilution (0.01%) is effective and relatively nonirritating when used as a miotic after the lens is removed in round pupil cataract extraction.
H, Beasley +3 more
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Learned aversions to intracerebral carbachol
Physiology & Behavior, 1977Abstract The learned taste aversion paradigm was employed to test for aversive effects of microinjections of carbachol to the medial septum, lateral ventricle and ventral hippocampus. To determine the locus of action of carbachol, either a central cholinergic blocker (atropine sulfate) or a peripheral cholinergic blocker (atropine methyl nitrate) was
R H, Myers, J M, De Castro
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2007
Carbachol is a structural analog of acetylcholine and has agonist activity at muscarinic and nicotinic cholinergic receptors. It is like acetylcholine in being a quaternary amine and having a positive charge at all pH values. A major difference from acetylcholine is that carbachol is not hydrolyzed by cholinesterases.
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Carbachol is a structural analog of acetylcholine and has agonist activity at muscarinic and nicotinic cholinergic receptors. It is like acetylcholine in being a quaternary amine and having a positive charge at all pH values. A major difference from acetylcholine is that carbachol is not hydrolyzed by cholinesterases.
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Pharmacological Studies on N-Demethylated Carbachol
Journal of Pharmaceutical Sciences, 1978In attempts to find a drug more active than pilocarpine, the tertiary nitrogen derivative of carbachol, N-demethylated carbachol, was synthetized and tested on several autonomic nervous system preparations. N-Demethylated carbachol was active at muscarinic and nicotinic sites in vivo and in vitro.
J, Trzeciakowski, C Y, Chiou
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Hyperthyroidism Protects Against Carbachol-Induced Bronchospasm
Chest, 1987We studied the effect of increased thyroid function on airway reactivity. Carbachol challenge was performed to assess airway reactivity according to a standardized method. Measurements of forced expiratory volume-1 second (FEV1), specific airway conductance (SGaw), the provocative dose of carbachol for a 20 percent decrease in FEV1 (PD-20) and that for
R H, Israel +4 more
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IR Spectrophotometric Assay of Carbachol Solutions
Journal of Pharmaceutical Sciences, 1977Carbachol ophthalmic solutions can be assayed by evaporating a measured volume, dissolving the residue in methanol, and scanning the carbonyl stretching frequency in an IR spectrophotometer using a cell with calcium fluoride windows. Methylcellulose and other formulation vehicle components do not interfere.
J, Frank, L, Chafetz
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Comparison of intraocular acetylcholine and carbachol
Journal of Cataract and Refractive Surgery, 1986Commercially available 1% acetylcholine chloride and 0.01% carbachol chloride, which are commonly used as miotics in intraocular surgery, have recently been reformulated. Comparative studies of these agents show similar miotic activity. However, in vitro perfusion of human corneas demonstrated that 1% acetylcholine chloride causes marked changes in ...
R W, Yee, H F, Edelhauser
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Determination of Carbachol in Aqueous Solution
Journal of Pharmaceutical Sciences, 1969A more specific method of analysis of carbachol (carbamylcholine chloride) in aqueous solution is reported. The procedure requires the chlorination of the free N—H moiety which in turn is utilized to oxidize iodide to iodine. Quantitation is then accomplished by reacting this latter product with starch and measuring the resultant blue color.
R, Puckett, R D, Poe
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Rapid activation of gluconeogenesis after intracerebroventricular carbachol
American Journal of Physiology-Endocrinology and Metabolism, 1989Intracerebroventricular administration of carbachol (27 nmol in 5 microliters 0.15 M NaCl) produced marked hyperglycemia in 24-h fasted rats, despite the negligible amounts of preformed liver glycosyl residues. To investigate the possibility of a stimulation of gluconeogenesis, conscious unrestrained rats were continuously infused with [14C]bicarbonate
R H, Migliorini +3 more
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