Results 201 to 210 of about 43,661 (255)

IR Spectrophotometric Assay of Carbachol Solutions

Journal of Pharmaceutical Sciences, 1977
Carbachol ophthalmic solutions can be assayed by evaporating a measured volume, dissolving the residue in methanol, and scanning the carbonyl stretching frequency in an IR spectrophotometer using a cell with calcium fluoride windows. Methylcellulose and other formulation vehicle components do not interfere.
J, Frank, L, Chafetz
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Comparison of intraocular acetylcholine and carbachol

Journal of Cataract and Refractive Surgery, 1986
Commercially available 1% acetylcholine chloride and 0.01% carbachol chloride, which are commonly used as miotics in intraocular surgery, have recently been reformulated. Comparative studies of these agents show similar miotic activity. However, in vitro perfusion of human corneas demonstrated that 1% acetylcholine chloride causes marked changes in ...
R W, Yee, H F, Edelhauser
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Determination of Carbachol in Aqueous Solution

Journal of Pharmaceutical Sciences, 1969
A more specific method of analysis of carbachol (carbamylcholine chloride) in aqueous solution is reported. The procedure requires the chlorination of the free N—H moiety which in turn is utilized to oxidize iodide to iodine. Quantitation is then accomplished by reacting this latter product with starch and measuring the resultant blue color.
R, Puckett, R D, Poe
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Rapid activation of gluconeogenesis after intracerebroventricular carbachol

American Journal of Physiology-Endocrinology and Metabolism, 1989
Intracerebroventricular administration of carbachol (27 nmol in 5 microliters 0.15 M NaCl) produced marked hyperglycemia in 24-h fasted rats, despite the negligible amounts of preformed liver glycosyl residues. To investigate the possibility of a stimulation of gluconeogenesis, conscious unrestrained rats were continuously infused with [14C]bicarbonate
R H, Migliorini, M A, Garofalo, J E, Roselino, I C, Kettelhut   +3 more
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Central hyperglycaemic effect of adrenaline and carbachol

Acta Endocrinologica, 1985
Abstract. The effect of chemical stimulation of the brain on glucoregulation was studied in anaesthetized rats. Adrenaline, noradrenaline, acetylcholine, dopamine and carbachol (5 × 10−8 mol/μl saline) were injected directly into the third cerebral ventricle and changes in hepatic venous plasma glucose, immunoreactive glucagon and insulin ...
A, Iguchi, H, Matsunaga, M, Gotoh, T, Nomura, A, Yatomi, N, Sakamoto   +5 more
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Atropine antagonism of carbachol-induced hyperglycemia

Journal of Pharmaceutical Sciences, 1967
Hyperglycemia was induced with carbachol in rats, rabbits, and dogs, and the effect in rabbits was shown to be dose related. In albino rabbits with negligible plasma esterase activity, atropine sulfate effectively prevented hyperglycemia following 25 mcg./Kg. of carbachol, and the effect appeared to be dose dependent.
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Central hyperglycemic effect of carbachol in rats

European Journal of Pharmacology, 1976
Intraventricular injection of carbachol produces hyperglycemia in rats at doses which are ineffective when given subcutaneously. This effect is suppressed by intraventricular administration of small amounts of atropine, further supporting the suggestion that the effect of carbachol is due to its action on central cholinergic receptors.
M, Korner, A, Ramu
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Effect of Carbachol on Rabbit Corneal Endothelium

Archives of Ophthalmology, 1987
We investigated the current reformulation of the commercially available intraocular preparation of carbachol for its effect on corneal thickness and endothelial cell ultrastructure. A 15-minute perfusion in the specular microscope with 0.01% carbachol caused a significant increase in the corneal swelling rate, which returned to control values after 75 ...
D B, Birnbaum, D S, Hull, K, Green, N P, Frey   +3 more
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Corneal Edema After Use of Carbachol

Archives of Ophthalmology, 1979
To the Editor. —In a recent issue of theArchives(96:1897-1901,1978) Vaughn et al described their experimental data on the perfusion of the anterior chamber of rabbits with carbachol. They noted transitory but reversible swelling of the cornea, which implied some transitory endothelium dysfunction.
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Effect of carbachol on postoperative intraocular pressure

Journal of Cataract and Refractive Surgery, 1988
Carbachol instilled in 125 eyes at the time of extracapsular cataract extraction and posterior chamber lens insertion had a statistically significant effect on lowering the postoperative intraocular pressure (IOP) at 24 hours (average IOP 14.0 mm Hg) and at 72 hours (average IOP 11.6 mm Hg) (P less than .001).
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