Results 121 to 130 of about 127,195 (275)

Synthetic Cathepsin B Sensitive Adjuvant‐Peptide Conjugates to Target Intracellular Toll‐Like Receptors 7 and 8

open access: yesChemistryEurope, EarlyView.
Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn   +6 more
wiley   +1 more source

Enantioselective Total Synthesis of (—)-Acetylaranotin, a Dihydrooxepine Epidithiodiketopiperazine [PDF]

open access: yes, 2012
The first total synthesis of the dihydrooxepine-containing epidithiodiketopiperazine (ETP) (−)-acetylaranotin (1) is reported. The key steps of the synthesis include an enantioselective azomethine ylide (1,3)-dipolar cycloaddition reaction to set the ...
Codelli, Julian A.   +2 more
core   +1 more source

Organophotoredox/Cobalt‐Catalyzed Retro‐Hydroformylation of Aldehydes

open access: yesChemistryEurope, EarlyView.
A new photoredox/cobalt retro‐hydroformylation is developed. This one‐pot two‐step process involves the in situ formation of the corresponding 1,4‐dihydropyridine as key intermediate. Under mild reaction conditions, alkenes are efficiently produced from a wide range of aliphatic α‐monosubstituted aldehydes, with high functional‐group tolerance.
Augustin Nouaille   +3 more
wiley   +1 more source

Solvent‐Driven Pore Engineering in Coffee‐Derived Activated Hydrochar: Implications for Post‐Combustion CO2 Capture

open access: yesCarbon Energy, EarlyView.
Solvent washing of coffee‐ground hydrochars produces activated carbons with tunable pore sizes while maintaining surface area. Removing non‐polar contaminants enhances microporosity, increasing CO2 uptake by 40%. Moderate pore sizes (9–12 Å) yield optimal CO2:N2 selectivity, whereas smaller pores reduce selectivity due to stronger interactions between ...
Muhammad Irfan Maulana Kusdhany   +4 more
wiley   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

open access: yesChemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Common substitution mutation F348Y of acetylcholinesterase gene contributes to organophosphate and carbamate resistance in Cimex lectularius and C. hemipterus

open access: hybrid, 2021
Osamu Komagata   +10 more
openalex   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

open access: yesChemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy