An Update: Enzymatic Synthesis for Industrial Applications
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer+4 more
wiley +1 more source
Redirecting the Peptide Cleavage Causes Protease Inactivation
Cysteine and serine proteases cleave peptides through covalent catalysis by generating a transient adduct with the N‐terminal part of the substrate after releasing its C‐terminal part. We demonstrate the unique redirection of this event leading to strong enzyme inactivation.
Michael Gütschow+20 more
wiley +1 more source
Metabolite essentiality elucidates robustness of Escherichia coli metabolism
Complex biological systems are very robust to genetic and environmental changes at all levels of organization. Many biological functions of Escherichia coli metabolism can be sustained against single-gene or even multiple-gene mutations by using ...
Almaas+23 more
core +2 more sources
Fluoride inhibition of wine yeasts : a thesis presented in partial fulfilment of the requirements for the degress of Master of Science in Microbiology at Massey University [PDF]
Stuck or slowed fermentations are costly in time and money to winemakers. There are many variables that can interrupt fermentation. One of the lesser known factors is the effect of fluoride on grape juice fermentations.
Clayton, Miranda Gaye
core
Three insecticides - the pyrethroid deltamethrin, the carbamate carbosulfan and the organophosphate chlorpyrifos-methyl - were tested on mosquito nets in experimental huts to determine their potential for introduction as malaria control measures.
Asidi+17 more
core +1 more source
Metal‐Mediated Protein Engineering within Live Cells
This review discusses how metal ions can mediate protein modification within live cells. With its easy handling, rapid solubility, and ease of internalization within the cells, metal ions can be an excellent stimulus for many organic reactions needed within an intracellular medium, which can modify proteins and lead to applications in chemistry ...
Pritam Ghosh
wiley +1 more source
Advances in Metal‐Free Transamidation: A Sustainable Approach to Amide Bond Formation
This review highlights the recent developments of transamidation reactions under metal‐free reaction conditions. Various amines including weak nucleophilic amines such as aromatic amines have been used to achieve the transamidation reactions under mild and relatively green reaction conditions. Abstract The amide functionalities are a crucial functional
Niharan Sivaraj+2 more
wiley +1 more source
FQPA IMPLEMENTATION TO REDUCE PESTICIDE RESIDUE RISKS: PART I: AGRICULTURAL PRODUCER CONCERNS [PDF]
The Food Quality Protection Act of 1996 (FQPA) transforms the regulation of pesticide residues on food in the United States. Three changes are prominent. First, under the FQPA, the U.S.
Batie, Sandra S.+2 more
core +1 more source
Reusable Selenenyl Iodide‐Initiated Cascade Cyclization of Polyenes with N‐terminating Groups
A cascade cyclization of polyenes with N‑terminating groups, initiated by an isolable selenenyl iodide, was developed. The cavity‑shaped substituent stabilized both the selenenyl iodide and the selenenic acid generated via β‑selenoxide elimination, enabling the regeneration of selenenyl iodide.
Satoru Kuwano+4 more
wiley +1 more source
Stereoselective Total Synthesis of (+)-Giganin and Its C10 Epimer by Using Late-Stage LithiationBorylation Methodology [PDF]
Alali+55 more
core +2 more sources