Results 181 to 190 of about 74,560 (387)

Total Synthesis of Kanamycins

Chemistry – A European Journal, EarlyView.
This paper reports on creating a novel synthetic route of kanamycins A and B using the desymmetric boron‐mediated aglycon delivery (BMAD) reaction of meso‐diol acceptor with 1,2‐anhydro donor and regio‐ and stereoselective glycosylation of diol acceptor with trichloroacetimidate donor for introduction of a set of challenging 1,2‐cis‐glycosidic linkages
Kanae Hosomi, Banjo Imai, Naoto Takemura, Kazuki Senoo, Chigusa Hayashi, Masayuki Igarashi, Kazunobu Toshima, Daisuke Takahashi   +7 more
wiley   +1 more source

Strategy‐Level Prodrug Synthesis

Chemistry – A European Journal, EarlyView.
Prodrug approaches can be expanded by increasing options for controlling site‐selective functionalization, boosting the range of linking groups, and enhancing the chemoselectivity of reactive group incorporation. This Concept describes strategy‐level prodrug synthesis, whereby these issues are addressed at an early stage of a sequence.
Paul J. Geaneotes, Paul E. Floreancig
wiley   +1 more source

Studies on Carbamates. XV. The Carbamates of alpha-Aminocaproic Acid, epsilon-Aminocaproic Acid and alpha,epsilon-Diaminocaproic Acid. [PDF]

, 1964
Mogens Ballund Jensen, Carl Faurholt, Kristian Larsson, Hans Halvarson, Lennart Nilsson   +4 more
openalex   +1 more source

Stimuli‐Responsive Prodrug Linkers That Simultaneously Release Cargo and Neutralize In Situ Generated (Aza)Quinone Methides

Chemistry – A European Journal, EarlyView.
Highly reactive (aza)quinone methides are electrophiles generated from many stimuli‐responsive prodrugs and probes. A new linker has been designed to quench the electrophilic methide, forming a tetrahydroisoquinoline (THIQ) heterocycle in high yields, even when a competing nucleophile is present.
Veera V. Shivaji R. Edupuganti, Siddharth S. Matikonda, Aggie Lawer, Jessica M. Fairhall, Harrison M. Lewin, Jui Thiang Brian Kueh, Joel D. A. Tyndall, Allan B. Gamble   +7 more
wiley   +1 more source

ASSESSMENT OF PESTICIDE RESIDUES IN CUCUMBER (Cucumis sativa) FRUITS FROM THREE MAJOR MARKETS IN THE AMANSIE WEST DISTRICT, GHANA

Food and Environment Safety
Cucumber (Cucumis sativa), a widely consumed vegetable, often faces issues with pests and diseases, leading to the excessive use of pesticides during its cultivation.
Evans Ntim AMEDOR, Robert Akayim AWASINA, John Yao AFETSU   +2 more
doaj  

The Initiating Action of Ethyl Carbamate (Urethane) on Mouse Skin

, 1955
I. Berenblum, Nechama Haran
openalex   +1 more source

First Phosphonic‐Type Inhibitors and Activity‐Based Probes Specific to the O'nyong‐nyong Virus Capsid Protease

ChemMedChem, EarlyView.
The serine capsid protease (CP) catalyzes a crucial process of the alphaviral replication cycle; therefore, it constitutes an interesting therapy target. Herein, the O'nyong‐nyong virus CP profile activity with a specific fluorogenic substrate is analyzed and examines the inhibitory activity of a new series of phosphonic analogs of tryptophan and ...
Karolina Torzyk‐Jurowska, Agnieszka Łupicka‐Słowik, Renata Grzywa, Yuliya Chykunova, Krzysztof Pyrć, Marcin Sieńczyk   +5 more
wiley   +1 more source

Improved C5‐Amide Bioisosteres for Human Neuraminidase 1 Inhibitors Based on 2‐Deoxy‐2,3‐Didehydro‐N‐Acetyl Neuraminic Acid

ChemMedChem, EarlyView.
This article describes the development of improved NEU1 inhibitors based on the 2‐deoxy‐2,3‐didehydro‐N‐acetyl neuraminic acid scaffold. A series of candidate inhibitors are designed containing bioisosteres of the C5‐amide group and evaluated for activity against NEU1‐4 enzymes.
Mostafa Radwan, Elisa G. Carvajal, Christopher W. Cairo   +2 more
wiley   +1 more source

Elucidating the structures of substituted adamantyl esters and ethers using rotational spectroscopy and computations

ChemPhysChem, Accepted Article.
Adamantane derivatives are promising candidates in the design of new materials with unique properties. In this study, we investigated the molecular structure of a series of adamantyl esters and ethers with an increasing substituent size using broadband rotational spectroscopy.
Nataša Burić, Donatella Loru, Jasna Alić, Marina Šekutor, Melanie Schnell, Pablo Pinacho   +5 more
wiley   +1 more source

Chromatography-free synthesis of carbamates from CO2 catalyzed by a green and recyclable biobased ionic liquid/Cu2O system

Journal of CO2 Utilization
Carbamates and related derivatives are crucial skeletons for pesticide design and pharmaceutical chemistry. Recently, a synthetic route for the production of carbamates has drawn great attention, which assembles the economical, renewable and non-toxic ...
Yanyan Gong, Yuankun Wang, Peng Li, Ye Yuan, Fangong Kong   +4 more
doaj