Results 11 to 20 of about 810 (205)

Targeting Monoacylglycerol Lipase in Pursuit of Therapies for Neurological and Neurodegenerative Diseases

Molecules, 2021
Neurological and neurodegenerative diseases are debilitating conditions, and frequently lack an effective treatment. Monoacylglycerol lipase (MAGL) is a key enzyme involved in the metabolism of 2-AG (2-arachidonoylglycerol), a neuroprotective ...
Anca Zanfirescu, Anca Ungurianu, Dragos Paul Mihai, Denise Radulescu, George Mihai Nitulescu   +4 more
doaj   +1 more source

Benzyl Carbamates of 4-Aminosalicylanilides as Possible BACE1 Modulators

Chemistry Proceedings, 2022
Recently, a series of thirty-eight 4-{[(benzyloxy)carbonyl]amino}-2-hydroxybenzoic acid amides designed as potential acetyl- and butyrylcholinesterase (AChE/BChE) inhibitors were described as potential drugs to alleviate the symptoms of Alzheimer’s ...
Petra Majerova, Dominika Pindjakova, Timotej Jankech, Ivana Gerhardtova, Jiri Kos, Andrej Kovac, Josef Jampilek   +6 more
doaj   +1 more source

Specific and rapid visual detection of organophosphorus and carbamate pesticides in agricultural products by gold nanoparticles conjugated with aptamer [PDF]

Journal of Crop Protection
Designing a fast, inexpensive, and easy method for on-site detection of pesticide residues is very important. In the present research, a sensitive nanobiosensor has been designed based on gold colloidal nanoparticles that could detect organophosphorus ...
Mohsen Morowati, Rahim Berahmand, Tahereh Tohidi Moghaddam   +2 more
doaj   +1 more source

QSTR Modeling to Find Relevant DFT Descriptors Related to the Toxicity of Carbamates

Molecules, 2022
Compounds containing carbamate moieties and their derivatives can generate serious public health threats and environmental problems due their high potential toxicity.
Emma H. Acosta-Jiménez, Luis A. Zárate-Hernández, Rosa L. Camacho-Mendoza, Simplicio González-Montiel, José G. Alvarado-Rodríguez, Carlos Z. Gómez-Castro, Miriam Pescador-Rojas, Amilcar Meneses-Viveros, Julián Cruz-Borbolla   +8 more
doaj   +1 more source

Clarifying an Electrometric Method for Determining Blood Cholinesterase Activity: A Scientific Letter [PDF]

Asia Pacific Journal of Medical Toxicology, 2022
In this scientific letter, a modified electrometric method is clarified for rapid and accurate determination of blood cholinesterase (ChE) activity in man and various animal species.
Fouad Mohammad
doaj   +1 more source

Quantification and Confirmation of Fifteen Carbamate Pesticide Residues by Multiple Reaction Monitoring and Enhanced Product Ion Scan Modes via LC-MS/MS QTRAP System

Molecules, 2018
In this research, fifteen carbamate pesticide residues were systematically analyzed by ultra-high performance liquid chromatography–quadrupole-linear ion trap mass spectrometry on a QTRAP 5500 system in both multiple reaction monitoring (MRM) and ...
Ying Zhou, Jian Guan, Weiwei Gao, Shencong Lv, Miaohua Ge   +4 more
doaj   +1 more source

An Overview of Pesticide Monitoring at Environmental Samples Using Carbon Nanotubes-Based Electrochemical Sensors

C, 2017
Carbon nanotubes have received enormous attention in the development of electrochemical sensors by promoting electron transfer reactions, decreasing the work overpotential within great surface areas.
Ademar Wong, Tiago A. Silva, Fábio R. Caetano, Márcio F. Bergamini, Luiz H. Marcolino-Junior, Orlando Fatibello-Filho, Bruno C. Janegitz   +6 more
doaj   +1 more source

Facile green approach towards the synthesis of some phenyl piperazine based dithiocarbamates as potent hemolytic and thrombolytic agents

Pakistan Journal of Pharmaceutical Sciences, 2021
The facile and efficient protocol for the synthesis of N-phenyl piperazine based di-thio-carbamates has been reported under neat conditions. A library of novel piperazine based di-thio-carbamates (3a-h) in excellent yields has been prepared. Solvent free,
Freeha Hafeez, Asim Mansha, Ameer Fawad Zahoor, Kulsoom Ghulam Ali, Samreen Gul Khan, Syed Ali Raza Naqvi   +5 more
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One-Pot Electrooxidative Allylation of Carbamates in the Presence of HBF4 and H2O

Electrochemistry
The one-pot electrooxidative allylation of carbamates was successfully demonstrated in the presence of HBF4 and H2O. Anodic oxidation of carbamates generated the corresponding α-hydroxylated intermediates in the presence of H2O.
Haruka HOMMA, Aika MOCHIZUKI, Kaori MIYAKOSHI, Natsumi HONJO, Misaki AKETO, Kohei FUNATSU, Toshiki TAJIMA   +6 more
doaj   +1 more source

Anti-Proliferative and Cytoprotective Activity of Aryl Carbamate and Aryl Urea Derivatives with Alkyl Groups and Chlorine as Substituents

Molecules, 2022
Natural cytokinines are a promising group of cytoprotective and anti-tumor agents. In this research, we synthesized a set of aryl carbamate, pyridyl urea, and aryl urea cytokinine analogs with alkyl and chlorine substitutions and tested their ...
Maxim Oshchepkov, Leonid Kovalenko, Antonida Kalistratova, Maria Ivanova, Galina Sherstyanykh, Polina Dudina, Alexey Antonov, Anastasia Cherkasova, Mikhail Akimov   +8 more
doaj   +1 more source