Results 191 to 200 of about 76,323 (380)

Beyond 2-Oxazolidinones: Access to <i>N</i>-Unsubstituted Six- and Seven-Membered Analogues Using CO₂ and Superbase Catalyst. [PDF]

Org Lett
Mannisto JK, Heikkinen J, Puumi J, Sahari A, Ramírez Veliz P, Repo T.   +5 more
europepmc   +1 more source

Clickable Pyclen‐Based Luminescent Lanthanide Complexes: Application to Two‐Photon Microscopy

Chemistry – A European Journal, EarlyView.
This work presents two pyclen‐based lanthanide complexes (Eu3+ and Sm3+) bearing an alkynyl‐linker dedicated to bioconjugation. Featuring strong luminescence and two‐photon (2P) absorption, they were conjugated to a cell‐penetrating peptide thanks to copper‐catalyzed azide‐alkyne cycloaddition. The resulting luminescent conjugates reach efficiently the
Baptiste Chartier, Nadège Hamon, Dina Akl, Annika Sickinger, Léo Corne, Guillaume Micouin, Akos Banyasz, Olivier Maury, Sule Erbek, Véronique Martel‐Frachet, Alexei Grichine, Maryline Beyler, Olivier Sénèque, Raphaël Tripier   +13 more
wiley   +1 more source

On Base-catalysed Reaction of Benzyl Carbamate with Formaldehyde

, 1969
Shigeya Takeuchi, Masayoshi Kinoshita, Ching-Yün Huang, Minoru Imoto   +3 more
openalex   +2 more sources

Targeting Ubiquitin‐Specific Protease 7 with Novel 5‐Amino‐Pyrazole Inhibitors: Design, Synthesis, and Biological Evaluation

ChemMedChem, EarlyView.
Ubiquitin‐specific protease 7 (USP‐7) is a novel target for anticancer therapy. To further extend the structure–activity relationships of the previously USP‐7 inhibitor STIRUR‐41, a library of 5‐aminopyrazoles is reported. 1d shows a potency comparable to lead compound STIRUR‐41 and promising in silico and in vitro pharmacokinetic properties ...
Matteo Lusardi, Elva Morretta, Andrea Spallarossa, Maria Chiara Monti, Camillo Rosano, Erika Iervasi, Marco Ponassi, Matteo Mori, Fiorella Meneghetti, Chiara Brullo   +9 more
wiley   +1 more source

Click-Triggered Bioorthogonal Bond-Cleavage Reactions. [PDF]

Top Curr Chem (Cham)
Keppel P, Hecko S, Mikula H.
europepmc   +1 more source

Analogs of Tuberin : Syntheses and Biological Activity of Some New 4-Methoxy Styryl Carbamates and 4-Methoxy Styryl Semicarbazones [PDF]

, 1978
J. D. RAMANATHAN, D. G. NAMBOOTHIRI, H. J. MEHTA, SWARNA S. SASTRY, A. C. PADHYA   +4 more
openalex   +1 more source

The [3,3]‐Sigmatropic Allyl Cyanate–Isocyanate Rearrangement on Levoglucosenone Derivatives Stereoselectively Provides 4‐Deoxy‐4‐Aminosugars

Chemistry–Methods, EarlyView.
The Ichikawa rearrangement of allyl cyanates obtained in situ from levoglucosenone‐derived allyl carbamates allows the synthesis of unique 4‐deoxy‐4‐amino‐d‐allose derivatives with complete chirality transfer in a metal‐free three‐step, one‐pot manner.
Debora Pratesi, Marta Rigacci, Beatriz Pava‐Gómez, Camilla Matassini, Andrea Goti, Cristina Faggi, Francesca Cardona   +6 more
wiley   +1 more source

Copper-Mediated Divergent Reactivity of Allene-Tethered Carbamates under Radical Conditions. [PDF]

Org Lett
Toledano-Pinedo M, Quirós MT, Padrón I, Halka D, Georgiou X, Martínez Del Campo T, Luna A, Almendros P.   +7 more
europepmc   +1 more source

Synthesis of New N,N′‐Diarylureas and Their Theoretical Study as Cannabinoid‐1 Receptor Inhibitors

ChemPlusChem, EarlyView.
A series of new pyrazolo‐ and triazolo‐based N,N′‐diarylureas is synthesized following the triphosgene protocol in the last step. Density functional theory calculations and molecular docking provide strong evidence that all new compounds bind strongly to the cannabinoid‐1 (CB‐1) receptor, showing comparable results with the known allosteric CB‐1 ...
Eirini Tsemperlidou, Nikitas Georgiou, Demeter Tzeli, Nikolaos Karousis, George Varvounis   +4 more
wiley   +1 more source

All-Heteroatom-Substituted Carbon Spiro Stereocenters: Synthesis, Resolution, Enantiomeric Stability, and Absolute Configuration. [PDF]

J Am Chem Soc
Viudes O, Besnard C, Siegle AF, Trapp O, Bürgi T, Pescitelli G, Lacour J.   +6 more
europepmc   +1 more source