Results 191 to 200 of about 350,350 (363)

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

Non‐Equilibrium Synthesis Methods to Create Metastable and High‐Entropy Nanomaterials

Advanced Science, EarlyView.
ABSTRACT Stabilizing multiple elements within a single phase enables the creation of advanced materials with exceptional properties arising from their complex composition. However, under equilibrium conditions, the Hume–Rothery rules impose strict limitations on solid‐state miscibility, restricting combinations of elements with mismatched crystal ...
Shuo Liu, Chaochao Dun, Jeffrey J. Urban, Mark T. Swihart   +3 more
wiley   +1 more source

Clinical Evaluation of 15% Carbamide Peroxide on the Surface Microhardness and Shear Bond Strength of Human Enamel [PDF]

, 2007
Michael J. Metz, Michael A. Cochran, Bruce A Matis, Cesar Gonzalez, J. A. Platt, Melvin R. Lund   +5 more
openalex   +1 more source

Metformin‐Based Covalent Organic Frameworks With Excellent Biosafety and High Efficiency against Pathogenic Microorganisms

Advanced Science, EarlyView.
This work presents the first metformin‐based COFs featuring built‐in biosafety and a unique triple‐synergy mechanism. This scalable platform achieves broad‐spectrum eradication of bacteria and viruses, enabling reusable protective membranes with exceptional biocompatibility for advanced biomedical applications and personal protection.
Jia‐Yi Liu, Hong Jiang, Lei Ma, Jin‐Yi Yu, Ming‐Yi Yang, Hao‐Ru Wang, Jun‐Yuang Tang, Shengfeng Huang, Wei Yi, Meng Lu, Ya‐Qian Lan, Xu‐Jia Hong   +11 more
wiley   +1 more source

Solar‐driven co‐evolution of H2 and H2O2 from pure water splitting over emerging photocatalysts: Detailed mechanism and future outlook

PhotoMat, EarlyView., 2023
Photocatalytic water splitting for co‐evolution of H2 and H2O2 is deemed as a sustainable and promising strategy to address energy and environment issues, thus receiving increasing attention and realizing continuous achievements. This review aims to offer a deep understanding of the mechanism for H2 and H2O2 co‐evolution and the design principle of ...
Qiaohong Zhu, Jiaqi Wu, Mengmeng Du, Ning Zhang, Bocheng Qiu   +4 more
wiley   +1 more source

A comparative study evaluates the effect of Hydrogen peroxide 38% and Carbamide peroxide 35% bleaching products on enamel microhardness (In vitro study)

, 2018
Reem Hassan Majeed
openalex   +2 more sources

Genotoxicity of 22% Carbamide Peroxide Bleaching Agent on Oral Cells using the Micronucleus Technique

, 2020
Laís Vargas Bonacina, Carolina do Amaral Vargas, Júlia Vanini, Júlia Zandoná, Rodrigo Rohenkohl Silva, Carmen Silvlvia Busin, Paula Benetti, João Paulo De Carli   +7 more
openalex   +1 more source

Effect of açaí sorbet on the color change of bovine teeth during bleaching with 10% carbamide peroxide: in situ and ex-vivo study [PDF]

, 2023
Silvia Pandolfo
openalex  

Defect‐Rich 2D Layered Double Hydroxides Enhance Sonodynamic Antibacterial Therapy

Advanced Science, EarlyView.
This study develops defect‐rich ultrathin ZnCuW‐LDH nanosheets (DR‐ZnCuW‐LDH) via acid etching. DR‐ZnCuW‐LDH exhibits fourfold enhanced US‐triggered ROS production due to oxygen defects and electronic modulation, demonstrating potent antibacterial efficacy in vitro/vivo.
Qian Liu, Yu Yang, Rui Zhao, Linwei Huang, Xingyu Qi, Min Wu, Jianliang Shen   +6 more
wiley   +1 more source

Whitening effectiveness of 10% and 15% carbamide peroxide on extrinsic discoloration by coffee

, 2018
A Hervin, Andi Soufyan, Bambang Irawan, N Matram   +3 more
openalex   +1 more source