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Therapeutic options for carbapenem-resistant Enterobacteriaceae infections [PDF]
Virulence, 2017 In recent years, carbapenem resistance among Enterobacteriaceae has dramatically increased and represents an important threat to global health. The optimal therapeutic management of carbapenem-resistant Enterobacteriaceae (CRE) infections has not been ...
Enrico Maria Trecarichi +1 more
exaly +4 more sources
The rapid spread of carbapenem-resistant Enterobacteriaceae [PDF]
Drug Resistance Updates, 2016 Carbapenems, our one-time silver bullet for multidrug resistant bacterial infections, are now threatened by widespread dissemination of carbapenem-resistant Enterobacteriaceae (CRE). Successful expansion of Enterobacteriaceae clonal groups and frequent horizontal gene transfer of carbapenemase expressing plasmids are causing increasing carbapenem ...
Robert F Potter +2 more
exaly +3 more sources
Carbapenem-resistant Enterobacteriaceae: biology, epidemiology, and management [PDF]
Annals of the New York Academy of Sciences, 2014 Introduced in the 1980s, carbapenem antibiotics have served as the last line of defense against multidrug‐resistant Gram‐negative organisms. Over the last decade, carbapenem‐resistant Enterobacteriaceae (CRE) have emerged as a significant public health threat.
Amos Adler +2 more
exaly +4 more sources
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Options for treating carbapenem-resistant Enterobacteriaceae
Current Opinion in Infectious Diseases, 2014To address the therapeutic management of carbapenem-resistant Enterobacteriaceae on the basis of literature of the last 12 months.Retrospective and prospective (nonrandomized noncontrolled) studies provide data regarding the management of infections due to carbapenem-resistant Enterobacteriaceae.
Petros I, Rafailidis, Matthew E, Falagas
openaire +2 more sources
Resistance Mechanism of Carbapenem-Resistant Enterobacteriaceae to Quinolones
Clinical Laboratory, 2021To investigate the epidemics of plasmid-mediated quinolone resistance (PMQR) gene in carbapenem-resistant Enterobacteriaceae (CRE) and the resistance mechanism.We collected CRE bacteria isolated clinically between December 2017 and December 2018 for identification and drug sensitivity testing using a VITEK2 Compact Analyzer.
Ming, Wei, Na, Tu, Kai, Yang
openaire +2 more sources
Statewide Surveillance of Carbapenem-Resistant Enterobacteriaceae in Michigan
Infection Control & Hospital Epidemiology, 2014Background.Carbapenem-resistant Enterobacteriaceae (CRE) are clinically challenging, threaten patient safety, and represent an emerging public health issue. CRE reporting is not mandated in Michigan.Methods.The Michigan Department of Community Health–led CRE Surveillance and Prevention Initiative enrolled 21 facilities (17 acute care and 4 long-term ...
Brenda M, Brennan +12 more
openaire +2 more sources
Optimizing therapy in carbapenem-resistant Enterobacteriaceae infections
Current Opinion in Infectious Diseases, 2018Purpose of review In the absence of randomized clinical trial data, questions remain regarding the optimal treatment of carbapenem-resistant Enterobacteriaceae (CRE) infections. CRE have historically been susceptible to polymyxins, tigecycline or
Tumbarello M. +2 more
openaire +2 more sources