Carbapenem-Resistant Enterobacteriaceae [PDF]
Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a major threat. Commonly used antibiotics are generally inactive against CRE. Therefore, timely detection of CRE is of paramount importance. Among CRE, those producing carbapenem-hydrolyzing β-lactamase enzymes (carbapenemase-producing Enterobacteriaceae) are particularly of concern because ...
Alina, Iovleva, Yohei, Doi
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Emerging superbugs: The threat of Carbapenem Resistant Enterobacteriaceae
Carbapenem-resistant Enterobacteriaceae (CRE) are gram-negative bacteria that are resistant to carbapenems, a group of antibiotics considered as the last-resource for the treatment of infections caused by multidrug-resistant bacteria.
Le Thanh Dong +2 more
doaj +3 more sources
Carbapenem Resistance In Enterobacteriaceae [PDF]
Carbapenem resistance is now a public health concern worldwide. Carbapenem is considered the last resort antimicrobial drug used for treatment of hospital care associated infection and community acquired infection that resistant to all other β-lactam drugs. There are a different mechanisms by which bacteria become resistant to carbapenem drug including
Radwa Farag +3 more
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Antibiotic Susceptibility Patterns for Carbapenem-Resistant Enterobacteriaceae. [PDF]
Carbapenem is a broad-spectrum beta-lactam antibiotic considered the last choice for the treatment of antibiotic-resistant Gram-negative bacteria. Thus, the increasing rate of carbapenem resistance (CR) in Enterobacteriaceae is an urgent public health threat.
Armin S +11 more
europepmc +4 more sources
Management of carbapenem-resistant Enterobacteriaceae infections [PDF]
Carbapenem resistance is defined as in vitro non-susceptibility to any carbapenem and/or documented production of a carbapenemase. This feature has rapidly spread worldwide among clinical isolates of Enterobacteriaceae, mostly Klebsiella spp., and is associated with diverse molecular mechanisms. Carbapenem resistance is often associated with resistance
Durante-Mangoni, Emanuele +2 more
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Carbapenem-Resistant Enterobacteriaceae: Epidemiology and Prevention [PDF]
Over the past 10 years, dissemination of Klebsiella pneumoniae carbapenemase (KPC) has led to an increase in the prevalence of carbapenem-resistant Enterobacteriaceae (CRE) in the United States. Infections caused by CRE have limited treatment options and have been associated with high mortality rates. In the previous year, other carbapenemase subtypes,
Neil, Gupta +3 more
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Carbapenem-Resistant Enterobacteriaceae Infections in Children [PDF]
Carbapenem-resistant Enterobacteriaceae (CRE) are an emerging global public health threat. Infections due to CRE are associated with significant morbidity and mortality. Few therapeutic options are available for treatment of these infections, and optimal antibiotic treatment regimens are unclear.
Kathleen, Chiotos +2 more
openaire +2 more sources
Systematic Review and Meta-Analysis of Clinical Efficacy and Safety of Meropenem-Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections. [PDF]
Bucataru A +7 more
europepmc +2 more sources
European intensive care physicians’ experience of infections due to antibiotic-resistant bacteria [PDF]
Background Antimicrobial resistance (AMR) compromises the treatment of patients with serious infections in intensive care units (ICUs), and intensive care physicians are increasingly facing patients with bacterial infections with limited or no adequate ...
De Waele, Jan +9 more
core +2 more sources
Carbapenem-Resistant Enterobacteriaceae Infections: Taiwan Aspects [PDF]
Carbapenem-resistant Enterobacteriaceae (CRE), a major resistance concern emerging during the last decade because of significantly compromising the efficacy of carbapenem agents, has currently become an important focus of infection control. Many investigations have shown a high association of CRE infections with high case-fatality rates.
Shio-Shin Jean +8 more
openaire +4 more sources

