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Plasmid diversity of <i>Serratia marcescens</i> and <i>Klebsiella pneumoniae</i> isolates involved in two carbapenem-resistant <i>Enterobacteriaceae</i> outbreaks in a Swiss hospital. [PDF]

Microbiol Spectr
Mauffrey F, Bertelli C, Greub G, Grandbastien B, Senn L, Blanc DS.   +5 more
europepmc   +1 more source

Proton pump inhibitors increase the risk of carbapenem-resistant Enterobacteriaceae colonization by facilitating the transfer of antibiotic resistance genes among bacteria in the gut microbiome. [PDF]

Gut Microbes
Lee I, Jo JW, Woo HJ, Suk KT, Lee SS, Kim BS.   +5 more
europepmc   +1 more source

The rapid spread of carbapenem-resistant Enterobacteriaceae [PDF]

Drug Resistance Updates, 2016
Carbapenems, our one-time silver bullet for multidrug resistant bacterial infections, are now threatened by widespread dissemination of carbapenem-resistant Enterobacteriaceae (CRE). Successful expansion of Enterobacteriaceae clonal groups and frequent horizontal gene transfer of carbapenemase expressing plasmids are causing increasing carbapenem ...
Alaric W D'souza, Gautam Dantas
exaly   +4 more sources

Carbapenem resistance in Enterobacteriaceae: here is the storm! [PDF]

Trends in Molecular Medicine, 2012
The current worldwide emergence of resistance to the powerful antibiotic carbapenem in Enterobacteriaceae constitutes an important growing public health threat. Sporadic outbreaks or endemic situations with enterobacterial isolates not susceptible to carbapenems are now reported not only in hospital settings but also in the community. Acquired class A (
Laurent Dortet, Laurent Poirel, Patrice Nordmann   +2 more
openaire   +2 more sources

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Options for treating carbapenem-resistant Enterobacteriaceae

Current Opinion in Infectious Diseases, 2014
To address the therapeutic management of carbapenem-resistant Enterobacteriaceae on the basis of literature of the last 12 months.Retrospective and prospective (nonrandomized noncontrolled) studies provide data regarding the management of infections due to carbapenem-resistant Enterobacteriaceae.
Matthew E. Falagas, Petros I. Rafailidis
openaire   +2 more sources

Optimizing therapy in carbapenem-resistant Enterobacteriaceae infections

Current Opinion in Infectious Diseases, 2018
Purpose of review In the absence of randomized clinical trial data, questions remain regarding the optimal treatment of carbapenem-resistant Enterobacteriaceae (CRE) infections. CRE have historically been susceptible to polymyxins, tigecycline or aminoglycosides (mostly gentamicin), and these antibiotics have long been ...
Tumbarello M., Losito A. R., Giamarellou H.   +2 more
openaire   +3 more sources

Resistance Mechanism of Carbapenem-Resistant Enterobacteriaceae to Quinolones

Clinical Laboratory, 2021
To investigate the epidemics of plasmid-mediated quinolone resistance (PMQR) gene in carbapenem-resistant Enterobacteriaceae (CRE) and the resistance mechanism.We collected CRE bacteria isolated clinically between December 2017 and December 2018 for identification and drug sensitivity testing using a VITEK2 Compact Analyzer.
Kai Yang, Ming Wei, Na Tu
openaire   +2 more sources

Carbapenem-Resistant Enterobacteriaceae: A Call for Cultural Change

Annals of Internal Medicine, 2014
Starting in 2011, a cluster of infections caused by carbapenem-resistant Enterobacteriaceae (CRE) occurred at the National Institutes of Health Clinical Center.
Tara N. Palmore, David K. Henderson
openaire   +3 more sources

Provider Role in Transmission of Carbapenem-Resistant Enterobacteriaceae

Infection Control & Hospital Epidemiology, 2017
OBJECTIVEWe sought to evaluate the role healthcare providers play in carbapenem-resistant Enterobacteriaceae (CRE) acquisition among hospitalized patients.DESIGNA 1:4 case-control study with incidence density sampling.SETTINGAcademic healthcare center with regular CRE perirectal screening in high-risk units.PATIENTSWe included case patients with ≥1 ...
Marika Grabowski, Kristen M. Wells, Amy J. Mathers, Costi D. Sifri, Jennifer M. Lobo, Hyojung Kang   +5 more
openaire   +3 more sources

Statewide Surveillance of Carbapenem-Resistant Enterobacteriaceae in Michigan

Infection Control & Hospital Epidemiology, 2014
Background.Carbapenem-resistant Enterobacteriaceae (CRE) are clinically challenging, threaten patient safety, and represent an emerging public health issue. CRE reporting is not mandated in Michigan.Methods.The Michigan Department of Community Health–led CRE Surveillance and Prevention Initiative enrolled 21 facilities (17 acute care and 4 long-term ...
Kerrie VerLee, Joseph R. Coyle, Keith S. Kaye, Martha S. Boehme, Daniel R. Sundin, Anurag N. Malani, Laraine Washer, Bryan O. Buckley, Noreen Mollon, Jennie Finks, Brenda M. Brennan, Jason M. Pogue, Dror Marchaim   +12 more
openaire   +3 more sources