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Options for treating carbapenem-resistant Enterobacteriaceae
Current Opinion in Infectious Diseases, 2014To address the therapeutic management of carbapenem-resistant Enterobacteriaceae on the basis of literature of the last 12 months.Retrospective and prospective (nonrandomized noncontrolled) studies provide data regarding the management of infections due to carbapenem-resistant Enterobacteriaceae.
Petros I, Rafailidis, Matthew E, Falagas
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Optimizing therapy in carbapenem-resistant Enterobacteriaceae infections
Current Opinion in Infectious Diseases, 2018Purpose of review In the absence of randomized clinical trial data, questions remain regarding the optimal treatment of carbapenem-resistant Enterobacteriaceae (CRE) infections. CRE have historically been susceptible to polymyxins, tigecycline or aminoglycosides (mostly gentamicin), and these antibiotics have long been ...
Tumbarello M. +2 more
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Resistance Mechanism of Carbapenem-Resistant Enterobacteriaceae to Quinolones
Clinical Laboratory, 2021To investigate the epidemics of plasmid-mediated quinolone resistance (PMQR) gene in carbapenem-resistant Enterobacteriaceae (CRE) and the resistance mechanism.We collected CRE bacteria isolated clinically between December 2017 and December 2018 for identification and drug sensitivity testing using a VITEK2 Compact Analyzer.
Ming, Wei, Na, Tu, Kai, Yang
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The Emerging Threat From Carbapenem‐Resistant Enterobacteriaceae
Nursing for Women's Health, 2013The emergence of carbapenem-resistant enterobacteriaceae (CRE) in the United States represents a serious danger to people who are hospitalized and is associated with case mortality rates as high as 50 percent. CRE infections have limited treatment options and the potential to spread widely if prevention and transmission measures are not employed ...
Jessica, Landry, Helen, Hurst
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Outcomes of carbapenem-resistant Enterobacteriaceae isolation: Matched analysis
American Journal of Infection Control, 2014Carbapenem-resistant Enterobacteriaceae (CRE) isolation is associated with poor outcomes. The matched cohort study design enables investigation of specific role of resistance in contributing to patients' outcomes. Patients with CRE were matched to 3 groups: (1) patients with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL), (2 ...
Christopher, Bogan +11 more
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Characteristics of carbapenem-resistant Enterobacteriaceae isolates from Korea
Diagnostic Microbiology and Infectious Disease, 2013In this study, the characteristics of carbapenem-resistant Enterobacteriaceae (CRE) isolates from Korea was investigated. A total of 22 CRE isolates were investigated, and most were identified as Klebsiella pneumoniae (16 isolates). In vitro antimicrobial susceptibility testing, multilocus sequence typing, and pulsed-field gel electrophoresis were ...
So Yeon, Kim +3 more
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Provider Role in Transmission of Carbapenem-Resistant Enterobacteriaceae
Infection Control & Hospital Epidemiology, 2017OBJECTIVEWe sought to evaluate the role healthcare providers play in carbapenem-resistant Enterobacteriaceae (CRE) acquisition among hospitalized patients.DESIGNA 1:4 case-control study with incidence density sampling.SETTINGAcademic healthcare center with regular CRE perirectal screening in high-risk units.PATIENTSWe included case patients with ≥1 ...
Marika E, Grabowski +5 more
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Carbapenem-resistant Enterobacteriaceae: An emerging bacterial threat
Seminars in Diagnostic Pathology, 2019The first reports of carbapenem resistance in Enterobacteriaceae isolates occurred in the early 1990s. Researchers published the first report of an isolate that produced Klebsiella pneumoniae carbapenemase in 2001. Since that time, carbapenemase-producing Enterobacteriaceae isolates have disseminated globally.
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Carbapenem-Resistant Enterobacteriaceae: A Call for Cultural Change
Annals of Internal Medicine, 2014Starting in 2011, a cluster of infections caused by carbapenem-resistant Enterobacteriaceae (CRE) occurred at the National Institutes of Health Clinical Center.
Tara N, Palmore, David K, Henderson
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