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Synthetic preparation of carbazoles can be challenging, requiring ring-building strategies and/or precious metal catalysts. Presented herein is a method for the preparation of carbazoles with the use of inexpensive and reliable hypervalent iodine ...
Addison M. Duda +3 more
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Novel Small-Molecule Hybrid-Antibacterial Agents against S. aureus and MRSA Strains
Ongoing resistance developments against antibiotics that also affect last-resort antibiotics require novel antibacterial compounds. Strategies to discover such novel structures have been dimerization or hybridization of known antibacterial agents.
Robin Gehrmann +5 more
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The p-TsOH-catalyzed Diels–Alder reaction of 3-(indol-3-yl)maleimides with chalcone in toluene at 60 °C afforded two diastereoisomers of tetrahydropyrrolo[3,4-c]carbazoles, which can be dehydrogenated by DDQ oxidation in acetonitrile at room temperature ...
Ren-Jie Fang +4 more
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Carbazole Derivatives as STAT Inhibitors: An Overview
The carbazole class is made up of heterocyclically structured compounds first isolated from coal tar. Their structural motif is preponderant in different synthetic materials and naturally occurring alkaloids extracted from the taxonomically related ...
Anna Caruso +5 more
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An Update of Carbazole Treatment Strategies for COVID-19 Infection
The Coronavirus disease 2019 (COVID-19) outbreak was declared by the World Health Organization (WHO) in March 2020 to be a pandemic and many drugs used at the beginning proved useless in fighting the infection. Lately, there has been approval of some new
Maria Grazia Bonomo +5 more
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Herein, we report the development of two new low‐cost 9‐(2‐ethylhexyl)‐9H‐carbazoles carrying the mono/dimethoxyphenyl substituted cyanovinylene units symmetrically at 3‐ and 6‐positions of the carbazole core (CZ1‐2), as potential hole‐transporting ...
Kavya S. Keremane +1 more
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A Nitrocarbazole as a New Microtubule-Targeting Agent in Breast Cancer Treatment
Breast cancer is still considered a high-incidence disease, and numerous are the research efforts for the development of new useful and effective therapies.
Maria Stefania Sinicropi +11 more
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Effect of Substituents of Cerium Pyrazolates and Pyrrolates on Carbon Dioxide Activation
Homoleptic ceric pyrazolates (pz) Ce(RR’pz)4 (R = R’ = tBu; R = R’ = Ph; R = tBu, R’ = Me) were synthesized by the protonolysis reaction of Ce[N(SiHMe2)2]4 with the corresponding pyrazole derivative.
Uwe Bayer +4 more
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The present work describes the effect of structural modification of carbazole‐based photosensitizers carrying carboxylic acid as a common anchoring functionality, on the photovoltaic parameters of newly fabricated DSSCs.
Praveen Naik +4 more
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4,7-Di(9H-carbazol-9-yl)-[1,2,5]oxadiazolo[3,4-d]pyridazine
Donor–acceptor–donor (D–A–D)-type molecules are considered as a promising class of NIR fluorescence materials. In this communication, 4,7-di(9H-carbazol-9-yl)-[1,2,5]oxadiazolo[3,4-d]pyridazine was obtained by dehydrogenation of 4,7-bis(1,2,3,4,4a,9a ...
Timofey N. Chmovzh +3 more
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