Results 111 to 120 of about 36,459 (348)

Heterogeneously Catalyzed Cascade Oxidative Coupling/Dearomative Spirocyclization of Diarylamines: Facile Access to Spiroacridines

Advanced Synthesis &Catalysis, EarlyView.
Abstract Spirocyclic compounds, particularly spirocyclohexadienones, are important in pharmaceuticals due to their biological activity. In this study, we develop a catalytic cascade oxidative spirocyclization of diarylamines for the rapid access to highly functionalized spirocyclohexadienones. Using commercially available recyclable heterogeneous metal
Kenji Matsumoto, Naho Sato, Yoshinori Kobayashi, Kanako Date, Yasuko Okamoto, Touya Kariya, Tsukasa Hirokane, Masahiro Yoshida   +7 more
wiley   +1 more source

Thienopyrrolo[3,2,1-jk]carbazoles: Building Blocks for Functional Organic Materials

Journal of Organic Chemistry, 2019
The facile preparation of three regioisomeric thienopyrrolo[3,2,1-jk]carbazoles applying a convenient C–H activation approach is presented. The incorporation of thiophene into the triarylamine framework significantly impacted the molecular properties in ...
Dorian Bader, J. Fröhlich, Paul Kautny
semanticscholar   +1 more source

Base-Promoted S_NAr Reactions of Fluoro- and Chloroarenes as a Route to N-Aryl Indoles and Carbazoles

Molecules, 2019
KOH/DMSO-promoted C-N bond formation via nucleophilic aromatic substitution (SNAr) between chloroarenes or fluoroarenes with indoles and carbazole under transition metal-free conditions affording the corresponding N-arylated indoles and carbazoles has ...
Muhammad Asif Iqbal, Hina Mehmood, Jiaying Lv, Ruimao Hua   +3 more
doaj   +1 more source

Development of Hydrofluoroolefin (HFO)‐based direct O‐fluoroalkenylation of phenols targeting tyrosine conjugation

Advanced Synthesis &Catalysis, Accepted Article.
Methodology for direct fluoroalkenylation of phenolic OH function was developed using a fluorinated electrophilic reagent derived from HFO1234ze gas. Besides various functionalized phenols, tyrosine and tyrosine‐based peptides were successfully conjugated under the optimized reaction conditions.
Rihárd Sisa, Ferenc Béke, Zoltán Novák   +2 more
wiley   +1 more source

Catalytic condensation for the formation of polycyclic heteroaromatic compounds

Nature Communications, 2018
The development of novel chemical reactions converting biomass-derived alcohols into important classes of compounds is a particularly attractive strategy.
Daniel Forberg, Tobias Schwob, Rhett Kempe   +2 more
doaj   +1 more source

Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives [PDF]

, 2014
Tumours of the central nervous system are intrinsically more dangerous than tumours at other sites, and in particular, brain tumours are responsible for 3% of cancer deaths in the UK. Despite this, research into new therapies only receives 1% of national
Akinaga, Alliance for Clinical Trials in Oncology, Arakawa, Arakawa, Awada, Barraja, Behrens, Boutros, Bradlow, Brain Tumour Research, Butowski, Camoratto, Cavazos, Cephalon, Chalmers, Chan, Chin, Chinni, Chris Sherer, Cleary, Davis, de Cresci Braga Montelli, Dekker, Deslandes, Deslandes, Diebold, Dowlati, Eckhardt, Evans, Evans, Fabbro, Faul, Fine, Frydoonfar, Frydoonfar, Galanis, Gilbert, Graff, Grose, Horton, Howells, Hudkins, Hudson, Hug, Hurwitz, Iyer, Jaszfold-Howorko, Jiang, Jones-Bolin, Kalkunte, Kaneko, Kase, Kojiri, Kreisl, Kristjansdottir, Lal, Langevin, Le Mée, Leppänen, Lewis, Lin, Lozano, Luo, Léonce, Magedov, Mahboobi, Marshall, Meggio, Merchant, Miknyoczki, Miknyoczki, Milhon, Nachshon-Kedmi, Nakano, Nathan, Nathan, Nelson, Nettleton, Norris, Ohmichi, Overmeyer, Overmeyer, Parsons, Peck, Pfizer, Prabhu, Prudent, Pundir, Rampling, Robinson, Ronnstrand, Rowinsky, Ruggeri, Saif, Satyan, Shen, Siegel, Singh, Stark, Tanaka, Timothy J. Snape, Tolcher, Toullec, Trabbic, Tutsch, Vassal, Walter, Weitman, Weng, Wick, Wick, Williams, Yamada, Yamashita, Yoshinari, Yoshinari, Yoshinari, Zheng   +117 more
core   +1 more source

Trait‐Based Life History Strategies Shape Bacterial Niche Breadth

Advanced Science, EarlyView.
This study investigates bacterial niche breadth through a large‐scale soil survey and over 2000 bacterial genomes. It identifies key life‐history traits—growth, competition, stress tolerance, resource acquisition, and dispersal—that correlate with niche breadth.
Ziheng Peng, Yiran Zhang, Xiaomeng Li, Hang Gao, Yu Liu, Yining An, Xun Qian, Gehong Wei, Shuo Jiao   +8 more
wiley   +1 more source

The synthesis of Benzo[C]carbazoles [PDF]

, 2006
Student Number : 9201775F - MSc dissertation - School of Chemistry - Faculty of ScienceThe base/light-induced cyclisation (condensation) reaction between alkyl and carbonyl substituents on biaryl compounds discovered in the University of the ...
Nhlapo, Johanna Mepeng
core  

Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition

Advanced Science, EarlyView.
This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang, Meng‐Die Li, Fan Pan, Wen‐Jia Lei, Yang Xi, Li‐Jun Ling, Leslie Myatt, Kang Sun, Wang‐Sheng Wang   +8 more
wiley   +1 more source

Study of TADF Emitters in OLEDs [PDF]

, 2015
Delayed fluorescence through thermally activated delayed fluorescence (TADF) has great potential for the creation of inexpensive and highly efficient white lighting applications, with superior colour rendering.
GRAVES, DAVID,RICHARD
core