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Antifungal Carbazoles

Current Medicinal Chemistry, 2009
Carbazole derivatives are well known for their various pharmacological activities, including anti-HIV, anticancer, antibacterial and antifungal activities. This review will focus on carbazoles that possess antifungal activity against Candida albicans, the major human fungal pathogen. In our search for new fungicidal compounds, we identified a series of
Karin, Thevissen   +4 more
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Antitumor Carbazoles

Anti-Cancer Agents in Medicinal Chemistry, 2007
Natural and synthetic carbazoles, either in a pure substituted or in an annellated substituted form, represent an important and heterogeneous class of anticancer agents, which has grown considerably over the last two decades. Many carbazole derivatives have been tested for cyctotoxic activity, some of them have entered clinical trials, but only ...
Asche, Christian, Demeunynck, Martine
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Polypyromellitimides based on carbazole and substituted carbazoles

European Polymer Journal, 1982
Abstract Polypyromellitimides have been synthesized from carbazole and N -benzylcarbazole by a two-step procedure involving ring-opening polyaddition with pyromellitic dianhydride and subsequent thermal cyclodehydration. The physicochemical, thermal and dielectric properties of the polymers have been studied. The various N -substituents, such as N
Mukul Biswas, Sukhendu K. Das
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Presence of carbazole and polyhalogenated carbazoles in human urine

Science of The Total Environment
Exposure to carbazole (CZ) and polyhalogenated carbazoles (PHCZs) may pose a threat to human health, owing to their potential dioxin-like toxicity. Until now, the presence of these chemicals in the human urine from the general population is still unclear.
Weili, Mao   +5 more
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Carbazole Alkaloids IV

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
D P, Chakraborty, Shyamali, Roy
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Benzannulation of Indoles to Carbazoles and Its Applications for Syntheses of Carbazole Alkaloids

Organic Letters, 2014
A novel and efficient method for the benzannulation of indoles to carbazoles is reported. γ-Carbonyl tert-butylperoxide is applied as a new diene building block for the π-extension of simple indoles. The synthetic utility of this method is demonstrated by concise and selective total syntheses of naturally occurring carbazole alkaloids, olivacine, and ...
Xiaojian, Zheng   +4 more
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Carbazoles

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Copper(II)-Catalyzed Iodinations of Carbazoles: Access to Functionalized Carbazoles

The Journal of Organic Chemistry, 2019
A copper-catalyzed iodination of carbazoles has been developed. Barluenga's reagent IPy2BF4 is used to generate a soft electrophilic halonium species for the iodination of the carbazoles. This report represents the first concept of copper-catalyst-promoted electrophilic halogenation of carbazoles.
Lukasz Przypis   +1 more
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Antioxidant effects of the highly-substituted carbazole alkaloids and their related carbazoles

Bioorganic & Medicinal Chemistry Letters, 2014
Antioxidant activities of 3-oxygenated and 3,4-dioxygenated carbazole alkaloids and their related carbazoles were comprehensively evaluated. In all assay systems, the 3,8-dihydroxycarbazoles carbazomadurin A (2) and B (3), and their synthetic precursors 2a and 3a exhibited higher antioxidant activities than the 3-monohydroxycarbazoles carazostatin (1),
Yuhzo, Hieda   +8 more
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Carbazole Alkaloids III

1991
The European dye stuff industry originally provided the main stimulus for development of the chemistry of carbazoles since the discovery of the first member of the group, carbazole (1) from coal tar in 1872 by Graebe and Glazer (35). The isolation of carbazole as a degradation product of strychnine (2) by Clemo and Perkin (18) in 1924 provided further ...
D P, Chakraborty, S, Roy
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